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  2. Lorlatinib may cause side effects such as12345:
    • Swelling in your arms, hands, legs, or feet
    • Numbness, tingling, or burning pain in your hands or feet
    • Mood changes
    • Feeling tired
    • Weight gain
    • Joint pain
    • Diarrhea
    • Tiredness
    • Constipation
    • Nausea / vomiting
    • Dizziness
    • Headache
    • Trouble sleeping
    • Vision changes (such as blurred vision, decreased vision)
    If any of these effects last or get worse, tell your doctor or pharmacist promptly3.
    Learn more:

    Common lorlatinib side effects may include: swelling in your arms, hands, legs, or feet; numbness, tingling, or burning pain in your hands or feet; mood changes; feeling tired; weight gain; joint pain; or diarrhea.

    Lorlatinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: weight gain muscle, joint, or back pain diarrhea constipation nausea vomiting
    medlineplus.gov/druginfo/meds/a619005.html

    Tiredness, constipation, nausea / vomiting, diarrhea, numbness/tingling of arms/legs, swelling ankles /feet/hands, dizziness, headache, trouble sleeping, weight gain, muscle/ joint pain, or vision changes (such as blurred vision, decreased vision) may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

    www.webmd.com/drugs/2/drug-176414/lorlatinib-or…

    The most common (20% or more) adverse reactions are edema, peripheral neuropathy, cognitive effects, dyspnea, cough, fatigue, weight gain, arthralgia, mood effects, and diarrhea.

    www.drugs.com/sfx/lorlatinib-side-effects.html

    Side effects that you should report to your doctor or health care professional as soon as possible:

    • allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
    • chest pain or tightness
    my.clevelandclinic.org/health/drugs/21330-lorlatini…
     
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