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  2. Respiratory failure
    • According to 2 sources
    Death is usually caused by respiratory failure. [ 19] The disease can affect people of any age, but usually starts around the age of 60. [ 19] The average survival from onset to death is two to four years, though this can vary, and about 10% of those affected survive longer than ten years.
    Death from ALS is usually caused by respiratory failure, due to the muscles that allow for breathing becoming paralyzed. Both non-invasive and invasive ventilation can ease breathing, but ALS will continue to progress.
     
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  6. Also known as: amyotrophic lateral sclerosis
    Content medically reviewed by
    Dr. Rakshith Bharadwajverified specialist
    MD, Internal Medicine
    View full profile onLinkedIn logoLinkedIn
    Causes

    • In most cases of Lou Gehrig’s disease, the cause is unknown. Suggested (but unproven) causes include:-
    • Gene mutations: Mutations in the DNA can lead to Lou Gehrig's disease
    • Protein mishandling
    • Autoimmune reactions
    • Possibly exposure to unknown environmental triggers
    • The risk factors include:
    • Heredity
    • Age - people with age of 40 to 60 years are at higher risk
    • Gender - men are more prone to develop Lou Gehrig's disease

    Symptoms
    Seek immediate medical attention if you experience symptoms.

    Symptoms of Lou Gehrig's disease are:

    • Weakness in your leg, feet or ankles
    • Difficulty walking or doing your normal daily activities
    • Hand Weakness or clumsiness
    • Slurred speech or trouble swallowing
    • Muscle cramps and twitching in your arms, shoulders, and tongue
    • Difficulty holding your head up or keeping good posture
    • Tripping and falling

    Complications

    The complications of ALS include:

    • Memory loss (dementia)
    • Difficulty in swallowing, leading to malnutrition, aspiration, and pneumonia (lung infection)
    • Difficulty in breathing, necessitating a tracheostomy; a procedure in which a hole is created in front of the neck to help with breathing
    • Weight loss

    Source: Focus Medica . For informational purposes only. Consult a medical professional for advice. Learn more
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