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- Prevent damagelyoprotectant (plural lyoprotectants) A substance added to something undergoing lyophilization in order to prevent damage.
en.wiktionary.org/wiki/lyoprotectant - People also ask
Clarifying the role of cryo- and lyo-protectants in the ... - PubMed
WEBMar 28, 2018 — Here, the conformational stability of a model protein, human growth hormone, is studied during freezing, and in the dried state as well, using molecular dynamics. The impact of the ice-water interface and of water removal is deeply …
- Author: Andrea Arsiccio, Roberto Pisano
- Publish Year: 2018
Effects of lyoprotectants on long-term stability and transfection ...
WEBMay 28, 2021 — We investigated the effect of lyoprotectants on the long-term stability and transfection efficiency of lyophilized (Lyo.) polyplexes prepared from poly (lactide-co …
- Author: Joshua Woo, Jeoung Soo Lee
- DOI: 10.2217/nnm-2021-0065
- Publish Year: 2021
- Published: 2021/04
- Studies of lyoprotectant meaning
Lyoprotectant Constituents Suited for Lyophilization and …
WEBFeb 2, 2024 — In this study, we aimed to identify an appropriate lyoprotectant composition for the lyophilization and reconstitution of stem-cell-derived EVs. MSC-derived EVs were …
Design of a new lyoprotectant increasing freeze-dried
WEBNov 12, 2021 — In this study, we evaluated the effect of a lyoprotectant containing sucrose + whey, sucrose + micellar casein or sucrose + inulin in comparison with a lyoprotectant …
What is Lyophilization? - NEB
WEBLyophilization is the creation of a stable preparation of a substance by freezing and dehydrating of the frozen product under high vacuum. Under controlled temperature and …
Bacterial Freeze Drying Protocol - OPS Diagnostics LLC
WEBLyophilization Medium - Bacteria need a lyoprotectant which helps them survive the freeze drying process. This medium can be very simple, such as 10% skim milk, or complicated …
The chemistry of lyophilized blood products - PMC - National …
WEBJul 7, 2018 — Concomitant to pre-hospital hemorrhage control, is the implementation of damage control resuscitation (DCR). DCR is characterized by the minimization of …
Use of Lyoprotectants in the Freeze-Drying of a Model Protein ...
WEBSucrose, Ficoll 70, and polyvinylpyrrolidone offered lyoprotection by preserving the enzymatic activity of the freeze-dried RNase. (Lyoprotection was defined as the …
LYOPHILIZATION definition and meaning | Collins English …
WEBLyophilization is the process of preserving something by freezing it very quickly and then subjecting it to a vacuum which removes ice. Lyophilization is one of the most effective …
Cryo- and lyoprotection of proteins: When the amino …
WEBAmino acids, sugars, and polyols are the main stabilizers used for cryo- and lyo-protection of proteins. In drying and freezing, the protein stabilization mechanisms by excipients are different. For instance, a good …
Lyoprotectant Optimization for the Freeze-Drying of …
WEBApr 21, 2020 — The lyoprotectant initially chosen for the freeze-dry of HIRMAb/pGL4 THLs was trehalose. However, this lyoprotectant did not prevent the fusion of the liposomes, release of plasmid DNA, and …
Lyophilization process optimization and molecular dynamics …
WEBOct 9, 2023 — Molecular dynamics simulation was used to compare the phospholipid molecular layer with the lyoprotectant in aqueous and anhydrous environments to …
Design of a new lyoprotectant increasing freeze-dried
WEBNov 12, 2021 — In this study, we evaluated the effect of a lyoprotectant containing sucrose + whey, sucrose + micellar casein or sucrose + inulin in comparison with a lyoprotectant …
Effects of lyoprotectants on long-term stability and transfection ...
WEBAim: We investigated the effect of lyoprotectants on the long-term stability and transfection efficiency of lyophilized (Lyo.) polyplexes prepared from poly (lactide-co-glycolide)-graft …
Devitrification of lyoprotectants: A critical determinant for ...
WEBNov 1, 2023 — Lyoprotectant. Devitrification. Storage. Stability. 1. Introduction. Bacteriophage as a natural preservative has been widely used in the food industry to …
For Lyophilization, Excipients Really Do Matter - BioPharm …
WEBJan 1, 2017 — Lyophilization, or freeze drying, is a well-recognized method for obtaining stable biologic drug products that have short shelf-lives in solution form. Lyophilized …
Freeze drying - Wikipedia
WEBFreeze drying, also known as lyophilization or cryodesiccation, is a low temperature dehydration process [1] that involves freezing the product and lowering pressure, …
Protective Effects of Cryoprotectants and Lyoprotectants on the ...
WEBThe effects of two common preservation methods on a bioactive metabolite producer, Streptomyces zagrosensis UTMC 1154, were studied. In the cryopreservation method, …
Influence of type and proportion of lyoprotectants on lyophilized ...
WEBMethods: Glucose, trehalose, sucrose, maltose, lactose, mannitol, inositol, hydroxypropyl-β-cyclodextrin and polyethylene glycol were used as single lyoprotectant and then …
WEBAbstract. Background: Stabilization of freeze‐dried lactic acid bacteria during long‐term storage is challenging for the food industry. Water activity of the lyophilizates is clearly …
WEBThe lyoprotectant solution is 75 electrospun into a fiber matrix that, when a biofluid sample is added, simultaneously absorbs the sample as it 76 dissolves and mixes with it.
Lyoprotectant Optimization for the Freeze-Drying of Receptor …
WEBJun 1, 2020 — The work shows that optimization of the lyoprotectant enables long-term storage of the MAb-targeted DNA encapsulated liposomes in the freeze-dried state. …
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