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- The Caenorhabditis elegans maternal-effect sterile genes, mes-2, mes-3, mes-4, and mes-6, encode nuclear proteins that are essential for germ-line development. They are thought to be involved in a common process because their mutant phenotypes are similar.
www.pnas.org/doi/10.1073/pnas.081016198 - People also ask
The phenotype of mes-2, mes-3, mes-4 and mes-6, maternal …
WEBWe hypothesize that the mes genes encode maternally supplied regulators of chromatin structure and gene expression in the germline and perhaps in somatic cells of the early embryo, and that at least some of their targets are on the X chromosomes.
- Author: Carol Garvin, Richard Holdeman, Susan Strome
- Publish Year: 1998
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Phenotype of mes-2, mes-3, mes-4 and mes-6, Maternal-Effect …
WEBJan 1, 1998 · Mutations in the four maternal-effect genes, mes-2, mes-3, mes-4, and mes-6, result in a common mutant phenotype: the hermaphrodite (XX) progeny of mes/mes …
The phenotype of mes-2, mes-3, mes-4 and mes-6, maternal …
WEBMutations in mes-2, mes-3, mes-4, and mes-6 result in maternal-effect sterility: hermaphrodite offspring of mes/mes mothers are sterile because of underproliferation …
Maternal effect genes: Update and review of evidence for a link …
WEBJan 1, 2022 · Maternal effect genes (MEGs) encode factors (e.g., RNA) that are present in the oocyte and required for early embryonic development. Hence, while these genes …
WEBThis review provides an updated summary of mammalian MEGs reported in the literature through early 2021, as well as an overview of the evidence for a link between MEGs and …
The Caenorhabditis elegans maternal-effect sterile proteins, MES …
WEBApr 24, 2001 · The Caenorhabditis elegans maternal-effect sterile genes, mes-2, mes-3, mes-4, and mes-6, encode nuclear proteins that are essential for germ-line …
WEBThe Caenorhabditis elegans maternal-effect sterile genes, mes-2, mes-3, mes-4, and mes-6, encode nuclear proteins that are essen-tial for germ-line development. They are …
Depletion of a Novel SET-Domain Protein Enhances the Sterility …
WEBNov 1, 2001 · Four maternal-effect sterile genes, mes-2, mes-3, mes-4, and mes-6, are essential for germline development in Caenorhabditis elegans. Homozygous mes …
The MES-2/MES-3/MES-6 Complex and Regulation of Histone …
WEBSep 21, 2004 · The phenotype of mes-2, mes-3, mes-4 and mes-6, maternal-effect genes required for survival of the germline in Caenorhabditis elegans, is sensitive to …
WEBresult in maternal-effect sterility: hermaphrodite offspring of mes mothers are sterile because of underproliferation and death of the germ cells, as well as an ab-
MES-2, a maternal protein essential for viability of the germline in
WEBJul 1, 1998 · mes-2 is a maternal-effect gene required for proliferation and survival of the germline in C. elegans. Our findings suggest that MES-2 is required for some aspect of …
Maternal effect genes: Update and review of evidence for a link …
WEBJan 13, 2022 · Maternal effect genes (MEGs) encode factors (e.g., RNA) that are present in the oocyte and required for early embryonic development. Hence, while these genes …
WEBThe genes encoding these essential maternal products are referred to as maternal effect genes (MEGs). MEGs accumulate maternal factors during oogenesis and enable ZGA, …
The Caenorhabditis elegans maternal-effect sterile proteins, MES …
WEBApr 4, 2001 · Our results suggest that the two C. elegans Polycomb group homologs (MES-2 and MES-6) associate with a novel partner (MES-3) to regulate germ-line …
MES-2, a maternal protein essential for viability of the germline in ...
WEBThe correct distribution of MES-2 requires the wild-type functions of mes-3 and mes-6. We hypothesize that mes-2 encodes a maternal regulator of gene expression in the early …
The phenotype of mes-2, mes-3, mes-4 and mes-6, maternal …
WEBMutations in mes-2, mes-3, mes-4, and mes-6 result in maternal-effect sterility: hermaphrodite offspring of mes/mes mothers are sterile because of underproliferation …
Evolutionary genetics of maternal effects - PMC - National Center …
WEBMar 29, 2016 · Maternal genetic effects (MGEs), where genes expressed by mothers affect the phenotype of their offspring, are important sources of phenotypic diversity in a …
Maternal effect - Wikipedia
WEBIn genetics, maternal effects occur when an organism shows the phenotype expected from the genotype of the mother, irrespective of its own genotype, often due to the mother …
The Caenorhabditis elegans maternal-effect sterile proteins, MES …
WEBMay 1, 2001 · Four maternal-effect sterile genes, mes-2, mes-3, mes-4, and mes-6, are essential for germline development in Caenorhabditis elegans.
Maternal H3K36 and H3K27 HMTs protect germline development …
WEBAug 3, 2022 · The H3K36 and H3K27 histone methyltransferases MES-4 and PRC2 protect survival of the nascent germline in Caenorhabditis elegans by repressing expression of …
What are maternal effects (and what are they not)? - PMC
WEBApr 4, 2009 · Although maternal effects were defined by quantitative geneticists well over half a century ago, there remains some confusion over exactly what phenomena should …
A maternal brain hormone that builds bone | Nature
WEB6 days ago · Our previous viral-mediated and genetic deletions of ERα in the ARC found that a subset of KISS1 neurons regulates bone mass and bone strength in females but …
Maternal APOE ε2 as a possible risk factor for elevated ... - PubMed
WEBJul 9, 2024 · Lead (Pb) is a global contaminant associated with multiple adverse health effects. Humans are especially vulnerable during critical developmental stages. During …
Maternal effect genes: Findings and effects on mouse embryo …
WEBJun 30, 2014 · Maternal effect genes (MEGs) refer to the genes whose products have little effect on oocyte development, maturation, ovulation, and fertilization, but which activate …
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