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  2. Methyltransferases are enzymes that will in the future enable clean and green alkylation of amino and hydroxy groups as well as reactive carbon atoms. These enzymes, their cofactor SAM (S -adenosylmethionine) and the opportunities’ they offer for new S N 2 chemistries are highlighted.

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    Methyltransferases are enzymes that will in the future enable clean and green alkylation of amino and hydroxy groups as well as reactive carbon atoms. These enzymes, their cofactor SAM (S -adenosylmethionine) and the opportunities’ they offer for new S N 2 chemistries are highlighted.

    chemistry-europe.onlinelibrary.wiley.com/doi/10.10…

    In this review the current state-of-the-art of S-adenosylmethionine (SAM)-dependent methyltransferases and SAM are evaluated. Their structural classification and diversity is introduced and key mechanistic aspects presented which are then detailed further.

    pubmed.ncbi.nlm.nih.gov/35691829/

    In this review, we will highlight the different classes of MTs (see section 2.), catalytic mechanisms of the methylation (see section 3.), SAM cofactor supply and regeneration, methyl acceptor diversity (see section 4.), and different applications of the methylation reaction for the production of APIs (see section 5.).

    chemistry-europe.onlinelibrary.wiley.com/doi/epdf/1…

    In this review the current state of the art of S-adenosylmethionine (SAM)-dependent methyltransferases and SAM are evaluated. Their structural classification and diversity is introduced and key mechanistic aspects presented which are then detailed further.

    discovery.ucl.ac.uk/id/eprint/10150643/

    Methyltransferases are a large group of enzymes that all methylate their substrates but can be split into several subclasses based on their structural features. The most common class of methyltransferases is class I, all of which contain a Rossmann fold for binding S -Adenosyl methionine (SAM).

    en.wikipedia.org/wiki/Methyltransferase
     
  3. Methyltransferases: Functions and Applications - PubMed

     
  4. Methyltransferases: Functions and Applications - UCL Discovery

  5. Methyltransferase - Wikipedia

    Methyltransferases are a large group of enzymes that all methylate their substrates but can be split into several subclasses based on their structural features. The most common class of methyltransferases is class I, all of which …

  6. Methyltransferases: Functions and Applications

  7. DNA Methyltransferases: From Evolution to Clinical …

    In animals, MTases are DNA methyltransferases (DNMTs), which have been reported in several functions on invertebrates and vertebrates. DNMTs are present in all animal phyla. DNMTs are functional in radial animals, …

  8. Methyltransferases: Functions and Applications. - Europe PMC

  9. Methyltransferases: Functions and Applications - Semantic Scholar

  10. Methyltransferases: Functions and Applications - TU Delft …

  11. DNA Methyltransferases - Role and Function

    Like the previous edition, this 2 nd edition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological …

  12. Biological functions of m6A methyltransferases - PMC

  13. Methyltransferase-Directed Labeling of Biomolecules and its …

  14. Methyltransferases: Key Regulators of Cellular Function

  15. Biological functions of m 6 A methyltransferases - PubMed

  16. "Methyltransferases: Functions and Applications"

  17. Tissue-specific roles of de novo DNA methyltransferases

  18. The expression landscape and clinical significance of …

  19. Methyl-dependent auto-regulation of the DNA N6-adenine ...

  20. Epitranscriptome profiles reveal participation of the RNA ...

  21. Carboxyl Methyltransferases: Natural Functions and Potential ...

  22. Carboxyl Methyltransferases: Natural Functions and Potential ...

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