53BP1 IHC - Search
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  1. Bokep

    https://viralbokep.com/viral+bokep+terbaru+2021&FORM=R5FD6

    Aug 11, 2021 · Bokep Indo Skandal Baru 2021 Lagi Viral - Nonton Bokep hanya Itubokep.shop Bokep Indo Skandal Baru 2021 Lagi Viral, Situs nonton film bokep terbaru dan terlengkap 2020 Bokep ABG Indonesia Bokep Viral 2020, Nonton Video Bokep, Film Bokep, Video Bokep Terbaru, Video Bokep Indo, Video Bokep Barat, Video Bokep Jepang, Video Bokep, Streaming Video …

    Kizdar net | Kizdar net | Кыздар Нет

  2. Abcam
    https://www.abcam.com/.../53bp1-antibody-ab21083

    Anti-53BP1 antibody (ab21083) | Abcam

    Rabbit Polyclonal 53BP1 antibody. Suitable for IHC-P, WB and reacts with Human, Mouse samples. Cited in 104 publications. Immunogen corresponding to Synthetic Peptide within Human TP53BP1.
     
  3. Thermo Fisher Scientific
    https://www.thermofisher.com/.../IHC-0…

    53BP1 Polyclonal Antibody (IHC-00001) | Thermo …

    WEBBethyl Laboratories Anti-53BP1 Polyclonal, Catalog # IHC-00001. Tested in Immunohistochemistry (IHC) applications. This antibody reacts with Human, Mouse samples. Supplied as 100 µL purified antibody (0.10 mg/mL).

  4. Abcam
    https://www.abcam.com/.../53bp1-antibody-ab36823

    Anti-53BP1 antibody (ab36823) | Abcam

  5. Studies of 53BP1 IHC
    National Center for Biotechnology Information
    53BP1: Keeping It under Control, Even at a Distance from DNA Damage
    Double-strand breaks (DSBs) are toxic lesions that can be generated by exposure to genotoxic agents or during physiological processes, such as during V(D)J recombination. The repair of these DSBs is crucial to prevent genomic instability and to maintain
    Author: Emilie Rass, S…
    Published: 2022/12
    Publication: Genes (B…
    National Center for Biotechnology Information
    53BP1 as a Potential Predictor of Response in PARP Inhibitor-Treated Homologous Recombination-Deficient Ovarian Cancer
    Multiple poly(ADP-ribose) polymerase (PARP) inhibitors (PARPis) have recently received regulatory approval for the treatment of ovarian cancer and are undergoing extensive clinical testing in additional homologous recombination (HR) deficient cancers,
    Author: Rachel M. Hurl…
    Published: 2019/04
    DOI: 10.1016/j.ygyno.2…
    PubMed
    Cancer-associated 53BP1 mutations induce DNA damage repair defects
    TP53 binding protein 1 (53BP1) plays an important role in DNA damage repair and maintaining genomic stability. However, the mutations of 53BP1 in human cancers have not been systematically examined. Here, we have analyzed 541 somatic mutations of 53BP1
    Author: Jiajia Zhang
    Published: 2021/03/31
    Keywords: 53BP1; Ca…
    National Center for Biotechnology Information
    p53 Binding Protein 53BP1 Is Required for DNA Damage Responses and Tumor Suppression in Mice
    53BP1 is a p53 binding protein of unknown function that binds to the central DNA-binding domain of p53. It relocates to the sites of DNA strand breaks in response to DNA damage and is a putative substrate of the ataxia telangiectasia-mutated (ATM) kinase.
    Author: Irene M. Ward…
    Published: 2003/04
    Publication: Mol Cell B…
    National Center for Biotechnology Information
    A role of the 53BP1 protein in genome protection: structural and functional characteristics of 53BP1-dependent DNA repair
    Nuclear architecture plays a significant role in DNA repair mechanisms. It is evident that proteins involved in DNA repair are compartmentalized in not only spontaneously occurring DNA lesions or ionizing radiation-induced foci (IRIF), but a specific
    Author: Eva Bártová, S…
    Published: 2019/04/04
    Publication: Aging (Al…
  6. Thermo Fisher Scientific
    https://www.thermofisher.com/antibody/primary/target/53BP1

    Anti-53BP1 Antibodies | Invitrogen | Thermo Fisher Scientific

  7. Cell Signaling Technology
    https://www.cellsignal.com/.../53bp1-antibody/4937

    53BP1 Antibody | Cell Signaling Technology

  8. Nature
    https://www.nature.com/articles/s41467-024-50999-2

    53BP1 loss elicits cGAS-STING-dependent antitumor immunity in …

  9. People also ask
    Which antibodies target 53BP1?
    These antibodies target 53BP1 in Human, Mouse, Rat, Non-human primate and Bat samples. Our 53BP1 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Knockdown and Cell treatment to confirm specificity to 53BP1.

    Anti-53BP1 Antibodies | Invitrogen - Thermo Fisher Scientific

    thermofisher.com
    Is 53BP1 a checkpoint protein?
    53BP1 belongs to a family of evolutionarily conserved DNA damage checkpoint proteins and is the vertebrate ortholog of the budding yeast Rad9 and fission yeast Crb2/Rhp9 checkpoint proteins. 53BP1 is a protein that consists of 1972 amino acids and lacks enzymatic activities directly implicated in DNA repair.

    A role of the 53BP1 protein in genome protection: structural

    ncbi.nlm.nih.gov
    What is the difference between 53bp1-rif1-ptip and brca1-ctip?
    These proteins are members of two protein complexes: 53BP1-RIF1-PTIP and BRCA1-CtIP, which make a “decision” determining whether canonical nonhomologous end joining (NHEJ) or homology-directed repair (HDR) is activated. It is generally accepted that 53BP1 mediates the NHEJ mechanism, while HDR is activated via a BRCA1-dependent signaling pathway.

    A role of the 53BP1 protein in genome protection: structural

    ncbi.nlm.nih.gov
    What is a 53BP1 cDNA fragment used for?
    A mouse 53BP1 cDNA fragment was used as a probe to isolate 53BP1 mouse genomic DNA from a mouse 129 genomic DNA phage library (Stratagene). The genomic DNA was cloned into pZErO-2 (Invitrogen), and the exon-intron structure characterized by restriction digestion, Southern blotting, and DNA sequencing.

    p53 Binding Protein 53BP1 Is Required for DNA Damage

    ncbi.nlm.nih.gov
    How is phosphorylated 53BP1 detected?
    The phosphospecific antibody against phospho-Ser25 and Ser29 of 53BP1 was used for western blotting to detect phosphorylated 53BP1. IR, ionizing radiation; shRNA, short hairpin RNA. We also examined other known ATM substrates such as SMC1, CHK2, KAP-1 and NBS1.

    Cell cycle-dependent inhibition of 53BP1 signaling by BRCA1

    nature.com
    Is 53BP1 a prognostic marker for cancer?
    Studies have reported various alterations in 53BP1 protein levels in different cancer specimens. Its expression has also been proposed as a prognostic marker for survival and/or response to various treatments [ 188 ]. Somatic mutations of 53BP1 in various cancer types have also been identified in cancer databases [ 189 ].

    53BP1: Keeping It under Control, Even at a Distance from DNA Damage …

    ncbi.nlm.nih.gov
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  10. Novus Biologicals
    https://www.novusbio.com/products/53…

    53BP1 Antibody - BSA Free | Novus Biologicals

    WEB146 rows · We currently stock just one antibody to phosphorylated 53BP1, which you can see at the following link: NB100-1803. This is guaranteed …

    • Reviews: 6
    • Novus Biologicals
      https://www.novusbio.com/primary-anti…

      53BP1 Antibodies | Novus Biologicals

      WEB53BP1 (p53 binding protein 1) plays a key role in response to DNA damage, checkpoint signaling during mitosis and enhancing TP53-mediated transcriptional activation. Browse our 53BP1 antibodies.

    • Novus Biologicals
      https://www.novusbio.com/products/53…

      53BP1 Antibody | BSA Free (NB100-304): Novus …

      WEB529 rows · View knockout-validated Rabbit Polyclonal anti-53BP1 Antibody - BSA Free (NB100-304). Validated Applications: WB, ChIP, Flow, Func, …

      • Reviews: 15
      • National Center for Biotechnology Information
        https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778356

        53BP1: Keeping It under Control, Even at a Distance from DNA …

      • fishersci.com
        https://www.fishersci.com/shop/products/53bp1-ihc...

        53BP1 IHC, Polyclonal, Bethyl Laboratories 100 μL; Unconjugated ...

      • Abcam
        https://www.abcam.com/en-us/products/primary...

        Anti-53BP1 antibody [EPR2172(2)] (ab175933) | Abcam

      • Santa Cruz Biotechnology
        https://www.scbt.com/p/53bp1-antibody-6b3e10

        53BP1 Antibody (6B3E10) | SCBT | Santa Cruz Biotechnology

      • National Center for Biotechnology Information
        https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430710

        53BP1 as a Potential Predictor of Response in PARP Inhibitor …

      • LSBio
        https://www.lsbio.com/antibodies/ihc-plus-tp53bp1...

        IHC-plus™ TP53BP1 / 53BP1 Polyclonal Antibody Rabbit anti …

      • Biomol GmbH - Life Science Shop
        https://www.biomol.com/.../anti-53bp1-ihc-ihc-00001-t

        Anti-53BP1 (IHC) | Bethyl Laboratories | Biomol.com

      • Nature
        https://www.nature.com/articles/s41598-021-82867-0

        Significance of abnormal 53BP1 expression as a novel molecular ...

      • Cell Signaling Technology
        https://www.cellsignal.com/products/primary...

        53BP1 Antibody (E7N5D) | Cell Signaling Technology

      • PubMed
        https://pubmed.ncbi.nlm.nih.gov/33359708

        Cancer-associated 53BP1 mutations induce DNA damage repair …

      • National Center for Biotechnology Information
        https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150747

        p53 Binding Protein 53BP1 Is Required for DNA Damage …

      • Abcam
        https://www.abcam.com/.../53bp1-antibody-ab172580

        Anti-53BP1 antibody (ab172580) | Abcam

      • National Center for Biotechnology Information
        https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519998

        A role of the 53BP1 protein in genome protection: structural and ...

      • Nature
        https://www.nature.com/articles/celldisc201519

        Cell cycle-dependent inhibition of 53BP1 signaling by BRCA1