Sepsis - Search
  1. Sepsis
    SepsisLife-threatening condition
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  2. Sepsis - Overview

    Verified Expert
    Also known as: blood poisoning
    An infection of the blood stream resulting in a cluster of symptoms such as drop in a blood pressure, increase in heart rate and fever.
    Condition Highlight
    Urgent medical attention is usually recommended by healthcare providers
    Condition Highlight
    Can be dangerous or life threatening if untreated
    How common is condition?
    Common (More than 200,000 cases per year in US)
    Is condition treatable?
    Treatable by a medical professional
    Does diagnosis require lab test or imaging?
    Requires lab test or imaging
    Time taken for recovery
    Can last several days or weeks
    Is condition preventable by vaccine?
    May be preventable by vaccine
    Condition Highlight
    Common for ages 60 and older
    Condition Highlight
    More common in males
    See more

    Causes

    Verified Expert

    • The cause of sepsis is bacterial, viral or fungal infection.
    • The risk factors include:
    • Weak immune system
    • Having diabetes or cirrhosis
    • Wounds or injuries such as burns

    See more

    Symptoms

    Verified Expert
    Seek immediate medical attention if you experience symptoms.

    Common symptoms include:

    • Generalized body swelling
    • Faster heart rate
    • Reduced urine output
    • Fever and chills
    • Decrease in platelet count
    • Difficulty in breathing
    • Mental confusion
    • Hyperventilation

    See more

    Treatment

    Verified Expert

    A number of medications are used to treat sepsis. The patient needs to be hospitalized. Mechanical ventilation may be required.

    Medication

    Antibiotics: These are administered intravenously; within the first 6 hours or earlier to the infection. Initially, the treatment starts with broad-spectrum antibiotic to treat a variety of bacteria.

    Ceftriaxone . Cefotaxime

    Vasopressors: If blood pressure remains too low after receiving intravenous fluids, they may be treated with vasopressors that constrict blood vessels and help increase the blood pressure.

    Norepinephrine

    Steroids: To reduce inflammation.

    Betamethasone

    See more
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    Microsoft Start Health

    Diagnosis

    Verified Expert
    One or more of these tests may be recommended by your medical provider.
    Diagnosing sepsis can be difficult because its signs and symptoms can be caused by other disorders. Physicians often use a pattern of tests to try to pinpoint the underlying infection.

    Common tests & procedures

    Blood test: Blood samples are tested for infections, clotting, oxygen availability, electrolyte imbalances and liver or kidney function

    Urine Test: Done to check for urinary tract infection.

    Wound culture test: To find out the suitable antibiotics that work best.

    Sputum culture test: To determine the type of germ causing the infection.

    X-ray: To check for infection in the lungs.

    Magnetic resonance imaging (MRI): To identify soft tissue infections.

    CT scan: CT scan of abdomen to check for infection in appendix, pancreas, or bowel area.

    Ultrasound: To check for infection in the gallbladder or ovaries.

    See more
    Source: Focus Medica. For informational purposes only. Consult a medical professional for advice. | Disclaimer: Opinions are from external health professionals and should not be considered as Microsoft's opinion or a substitute for professional help. Consult a health professional for medical advice.
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  2. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/sepsis

    Sepsis - Symptoms & causes - Mayo Clinic

     
  3. Cleveland Clinic
    https://my.clevelandclinic.org/health/dis…

    Sepsis: Symptoms, Causes, Treatment & Prevention

    Jan 19, 2023 — Sepsis is a life-threatening reaction to an infection that causes inflammation, organ damage and blood clots. Learn how to recognize the signs, risk factors and treatments of sepsis, and how to prevent complications.

  5. Wikipedia
    https://en.wikipedia.org/wiki/Sepsis

    Sepsis - Wikipedia

    Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4] [7] This initial stage of sepsis is followed by suppression of the immune system. [8] …

  6. Healthline
    https://www.healthline.com/health/sepsis

    Sepsis: Symptoms, Causes, Treatment, Risks, and …

    Feb 8, 2023 — Sepsis is a life threatening illness caused by your body’s response to an infection. Sepsis occurs when your body’s immune system response gets out of control, triggering extensive inflammation.

  7. Sepsis

    Also known as: blood poisoning
    Content medically reviewed by
    Dr. Karthikeya T Mverified specialist
    MD, Internal Medicine
    View full profile onLinkedIn logoLinkedIn
    An infection of the blood stream resulting in a cluster of symptoms such as drop in a blood pressure, increase in heart rate and fever.
    Condition Highlight
    Urgent medical attention is usually recommended by healthcare providers
    Condition Highlight
    Can be dangerous or life threatening if untreated
    How common is condition?
    Common (More than 200,000 cases per year in US)
    Is condition treatable?
    Treatable by a medical professional
    Does diagnosis require lab test or imaging?
    Requires lab test or imaging
    Time taken for recovery
    Can last several days or weeks
    Is condition preventable by vaccine?
    May be preventable by vaccine
    Condition Highlight
    Common for ages 60 and older
    Condition Highlight
    More common in males
    Condition Image
    Source: Focus Medica . For informational purposes only. Consult a medical professional for advice. Learn more
    Was this helpful?
  8. People also ask
    What causes sepsis?
    Bacterial infections are one of the most common causes of sepsis. Fungal, parasitic and viral infections are also potential sepsis causes. You can get sepsis when an infection triggers a chain reaction throughout your body causing organ dysfunction. The infection leading to sepsis can start in many different parts of the body.

    Sepsis: Symptoms, Causes, Treatment & Prevention - Cleveland Clinic

    my.clevelandclinic.org
    Why is sepsis a medical emergency?
    Sepsis occurs when your immune system has a dangerous reaction to an infection. It causes extensive inflammation throughout your body that can lead to tissue damage, organ failure and even death. Many different kinds of infections can trigger sepsis, which is a medical emergency. The quicker you receive treatment, the better your outcome will be.

    Sepsis: Symptoms, Causes, Treatment & Prevention - Cleveland Clinic

    my.clevelandclinic.org
    How does sepsis affect the body?
    The infection-fighting processes turn on the body, causing the organs to work poorly. Sepsis may progress to septic shock. This is a dramatic drop in blood pressure that can damage the lungs, kidneys, liver and other organs. When the damage is severe, it can lead to death. Early treatment of sepsis improves chances for survival.

    Sepsis - Symptoms & causes - Mayo Clinic

    mayoclinic.org
    What is bacterial sepsis?
    StatPearls [Internet]. Benjamin Bullock; Michael D. Benham. Last Update: May 21, 2023. Bacterial sepsis is a life-threatening condition that arises when the body's response to an infection injures its tissues and organs. Sepsis is caused by conditions that threaten the functional integrity of the host, such as microbial invasion.

    Bacterial Sepsis - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
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  9. Interesting reads - Sepsis

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  10. CDC
    https://www.cdc.gov/sepsis/about

    About Sepsis | Sepsis | CDC - Centers for Disease Control and …

  11. WHO
    https://www.who.int/.../fact-sheets/detai…

    Sepsis - World Health Organization (WHO)

    May 3, 2024 — Common signs of sepsis include fever, fast heart rate, rapid breathing, confusion and body pain. It can lead to septic shock, multiple organ failure and death. Sepsis is usually caused by bacterial infections but may be …

  12. WebMD
    https://www.webmd.com/a-to-z-guides/sepsis...

    Sepsis Symptoms and Treatment - WebMD

  13. CDC
    https://www.cdc.gov/sepsis

    Sepsis | Sepsis | CDC - Centers for Disease Control …

    Hospital Sepsis Program Core Elements. Monitor and optimize hospital management and outcomes of sepsis. Sepsis is a medical emergency. Learn the risks, spot the signs and symptoms, and act fast. Sepsis survivors: use these …

  14. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/...

    Sepsis - Diagnosis & treatment - Mayo Clinic

  15. CDC
    https://www.cdc.gov/sepsis/hcp/clinica…

    Caring for Patients with Sepsis | Sepsis | CDC

    Mar 8, 2024 — Sepsis is a medical emergency. You play a critical role. Protect your patients by acting fast. You should immediately evaluate and treat patients who might have sepsis. With your fast recognition and treatment, most …

  16. MedlinePlus
    https://medlineplus.gov/sepsis.html

    Sepsis: MedlinePlus

    Nov 13, 2023 — Sepsis is a life-threatening reaction to an infection that can cause organ failure and death. Learn about the causes, symptoms, diagnosis, treatment, and prevention of sepsis from MedlinePlus, a trusted health …

  17. BMJ Best Practice
    https://bestpractice.bmj.com/topics/en-gb/3000098

    Sepsis in adults - Symptoms, diagnosis and treatment - BMJ Best …

    Systemic lupus erythematosusNov 5, 2020
    Sepsis in children - Emerging treatments | BMJ Best Practice
    Sepsis in adults - Management ...
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  18. Verywell Health
    https://www.verywellhealth.com/early-signs-of-sepsis-5498608

    Early Signs of Sepsis: Symptoms and When to Seek Care

  19. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429642

    Sepsis: The evolution in definition, pathophysiology, and …

  20. NHS
    https://www.nhs.uk/conditions/sepsis

    Symptoms of sepsis - NHS

  21. UpToDate
    https://www.uptodate.com/contents/sepsis-syndromes...

    Sepsis syndromes in adults: Epidemiology, definitions ... - UpToDate

  22. MDCalc
    https://www.mdcalc.com/calc/1096

    SIRS, Sepsis, and Septic Shock Criteria - MDCalc

  23. National Institute of General Medical Sciences
    https://www.nigms.nih.gov/education/fact-sheets/Pages/sepsis.aspx

    Sepsis - National Institute of General Medical Sciences

  24. healthdirect
    https://www.healthdirect.gov.au/sepsis-septicaemia

    Sepsis - what it is and triggers like septicaemia and blood …

  25. Yale Medicine
    https://www.yalemedicine.org/conditions/sepsis

    Sepsis > Fact Sheets > Yale Medicine

  26. WHO
    https://www.who.int/health-topics/sepsis

    Sepsis - World Health Organization (WHO)

  27. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK537054

    Bacterial Sepsis - StatPearls - NCBI Bookshelf

    May 21, 2023 — Bacterial sepsis is a life-threatening condition that arises when the body's response to an infection injures its tissues and organs. Sepsis is caused by conditions that threaten the functional integrity of the host, such as …

  28. NHS inform
    https://www.nhsinform.scot/.../blood-and-lymph/sepsis

    Sepsis | NHS inform