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Biliary Obstruction - StatPearls - NCBI Bookshelf
- Published: 2022/11/26
- Authors: Ethan M. Coucke, Hina Akbar, Arslan Kahloon, P…
- Affiliations: McLaren Health Care, University of Tennesse…
Biliary obstruction commonly refers to blockage of the bile duct system, leading to impaired bile flow from the liver into the intestinal tract. Bile is a substance that contains bile salts, bilirubin, and cholesterol and is continuously synthesized in the liver hepatocytes. Bile is then transported...Biliary Obstruction Workup: Laboratory Studies, Imaging
- Regardless of the cause of cholestasis, serum bilirubin values (especially direct) are usually elevated. However, the degree of hyperbilirubinemia cannot help reliably distinguish between the causes of obstruction. Extrahepatic obstruction This is typically associated with considerable direct and indirect bilirubin elevation. However, in the early ...
Obstructive jaundice (summary) | Radiology Reference Article ...
Mar 24, 2019 · Ultrasound is the first line investigation for the assessment of jaundice. It is a quick and cheap test and effective in diagnosing biliary dilatation in the hands of an experienced …
Evaluation of Jaundice in Adults - AAFP
Initial laboratory evaluation should include assays for bilirubin (total and fractionated), a complete blood cell count, aspartate transaminase, alanine transaminase, gamma-glutamyltransferase,...
Diagnostic approach to patients with cholestatic jaundice - PMC
Laboratory work-up for cholestatic jaundice should include complete blood count with differential, urea, creatinine, electrolytes, and a liver panel including alkaline phosphatase, GGT, …
Jaundice in adults can be an indicator of significant underlying disease. It is caused by elevated serum bilirubin levels in the unconjugated or conjugated form. The evaluation of...
Jaundice - Clinical Methods - NCBI Bookshelf
Patients with obstructive jaundice often have clay-colored stools. A jaundiced patient with a positive reaction for blood in a clay-colored stool suggests carcinoma of the pancreas or …
Jaundice laboratory findings - wikidoc
Very high GGT levels (x 10 normal) may suggest biliary obstruction and hepatic malignancies as the underlying disease for jaundice. Raised GGT with raised alkaline phosphatase (more than …
Obstructive Jaundice is caused by intraluminal, luminal and extraluminal processes obstructing the bile ducts leading to an accumulation of conjugated bilirubin within the blood stream....
19.6: Hepatic and Biliary Disorders - Medicine LibreTexts
1 day ago · Obstructive jaundice is caused by an obstruction preventing biliary drainage. The most common cause of obstructive jaundice is a gallstone blocking the common bile duct, but it can …
Obstructive jaundice often produces pruritus, pale stools, and dark colored urine. Abdominal pain along with fevers and jaundice is suggestive of obstruction with an associated infection known …
Approach to the Patient with Jaundice & Abnormal Liver Tests
Cirrhosis can be diagnosed on the basis of two physical findings (asterixis, ascites) and two laboratory findings (decreased serum albumin [<2.8 g/dL], prolonged prothrombin time [INR …
Advances in the investigation of obstructive jaundice - PubMed
This article reviews advances in the investigation of obstructive jaundice, highlighting recent developments, many of which at present remain restricted to large centres of expertise, but …
Pathophysiological consequences and treatment strategy of …
Jaundice manifests as a yellowish pigmentation of the skin and sclera, which is caused by interrupted or impaired excretion of bilirubin and biliverdin. Obstructive jaundice (OJ), i.e., …
Role of MRCP to determine the etiological spectrum, level and …
The aim of this study is to evaluate the role of MRCP in the determination of the etiological spectrum, to evaluate level and degree of biliary obstruction in cases of obstructive jaundice, …
In this review, we highlight the imaging aspects that should be evaluated and reported by a radiologist when evaluating a patient planned for biliary drainage.
Biliary obstruction results in PD-1-dependent liver T cell …
Intrahepatic inflammation and liver T cell dysfunction due to obstructive jaundice are both ameliorated through abrogation of PD-1 expression. Biliary obstruction is a common clinical …
Obstructive Jaundice - SpringerLink
The laboratory evaluation includes a total bilirubin level; a level higher than 10 mg/dl usually indicates a malignant process whereas a level less than 10 mg/dl may be found in patients …
Diagnostic accuracy of ultrasonography in adults with obstructive …
Eighty adult patients with clinical and biochemical features of obstructive jaundice were enrolled in this study. The causes, degrees and levels of ductal obstruction were evaluated …
Ursodeoxycholic acid protects against sepsis-induced acute …
Jan 30, 2025 · Besides the hepatoprotective effects, the reno-protective effects of UDCA has been also verified in cisplatin-induced kidney injury , gentamicin-induced nephrotoxicity , obstructive …
Biliary metallic stent combined with radioactive 125I seeds …
4 days ago · Background To evaluate the safety and efficacy of biliary metallic stent (BMS) combined with radioactive 125I seed strands (RISS) for malignant hilar obstruction (MHO). …
Jaundice: an important, poorly recognized risk factor for …
Results: Preoperative jaundice, age, positive node status, poor differentiation and lymphatic invasion were significant indicators of poor outcome in multivariate analysis. Absence of …
Nifedipine Extended-Release Tablets For Oral Use - DailyMed
DESCRIPTION. Nifedipine is a drug belonging to a class of pharmacological agents known as the calcium channel blockers. Nifedipine is 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl …
Gallbladder Cancer Presenting with Jaundice: Uniformly Fatal or …
Jaundice as a presenting symptom of gallbladder cancer has traditionally been considered to be a sign of advanced disease, inoperability, and poor outcome. However, recent studies have …