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- In people with type 2 diabetes, retatrutide showed clinically meaningful improvements in glycaemic control and robust reductions in bodyweight, with a safety profile consistent with GLP-1 receptor agonists and GIP and GLP-1 receptor agonists. These phase 2 data also informed dose selection for the phase 3 programme.www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01053-X/fulltext
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Lilly's phase 2 retatrutide results published in The New England ...
Jun 26, 2023 — Lilly's phase 2 retatrutide results published in The New England Journal of Medicine show the investigational molecule achieved up to 17.5% mean weight reduction at …
American Diabetes Association Highlights Novel Agent …
Jun 26, 2023 — The findings showed that participants with T2D lowered their HbA1c by 1.3% to 2.0% after taking 4- 12 mg retatrutide for about six months, compared to no change with …
Triple hormone receptor agonist retatrutide for metabolic ... - Nature
Jun 10, 2024 — Phase 2 clinical trial results show that retatrutide, a triple agonist of the GIP, GLP-1 and glucagon receptors, results in up to 82% reduction in liver fat.
Retatrutide, a GIP, GLP-1 and glucagon receptor …
Retatrutide, a single peptide with agonist activity at the glucose-dependent insulinotropic polypeptide (GIP), GLP-1, and glucagon receptors, showed clinically meaningful glucose-lowering and bodyweight-lowering efficacy in …
Jun 26, 2023 — In this phase 2 trial, once-weekly treatment with retatrutide resulted in substantial weight reduction at 24 and 48 weeks, with dose-depen-dent efficacy. The results warrant further...
Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A …
Aug 10, 2023 — Results: We enrolled 338 adults, 51.8% of whom were men. The least-squares mean percentage change in body weight at 24 weeks in the retatrutide groups was -7.2% in …
Triple–Hormone-Receptor Agonist Retatrutide for Obesity
Oct 25, 2023 — To the Editor: Jastreboff and colleagues (Aug. 10 issue) 1,2 describe the results of their phase 2 trial of retatrutide, an agonist of three G-protein–coupled receptors, which led to …
American Diabetes Association Highlights Novel Agent …
Jun 26, 2023 — The results indicate that retatrutide has an overall safety and tolerability profile similar to other nutrient-stimulated hormone-based therapies, such as GLP-1 receptor agonists...
ESC 2024: Retatrutide improves lipid and …
4 days ago — This morning at the European Society of Cardiology (ESC) Congress 2024, Eli Lilly and Co announced the most recent trial results for retatrutide related to cardiovascular risk factors.
Triple Agonist Retatrutide Associated with Weight …
Jun 27, 2023 — Lilly’s Phase 2 retatrutide results published in the New England Journal of Medicine show the investigational molecule achieved up to 17.5% mean weight reduction at 24 weeks in adults with obesity and overweight.
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Nov 13, 2023 — The 48-week liver study demonstrated an average weight loss of 23.8% and 25.9% for patients taking 8mg and 12mg of retatrutide, respectively. The U.S. Food and Drug …
Lilly's phase 2 retatrutide results published in The New England ...
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Aug 12, 2023 — Retatrutide, a single peptide with agonist activity at the glucose-dependent insulinotropic polypeptide (GIP), GLP-1, and glucagon receptors, showed clinically meaningful …
Unleashing the power of retatrutide: A possible triumph over …
Feb 5, 2024 — Ongoing phase 3 trials, known as Triumph trials, 17 are evaluating the long‐term safety profile and effectiveness of retatrutide for lowering weight, osteoarthritis, and obstructive …
Results. at 24 weeks at all doses of retatrutide was greater than that with pla-cebo. Weight loss w. Safety: Gastrointestinal adverse events occurred substan-tially more often with...
The Lancet study unveils exciting findings on retatrutide as a …
Jun 29, 2023 — The study aimed to evaluate the efficacy and safety of a range of doses of retatrutide, a novel single peptide with activity against three receptor agonists, glucose …
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Jun 27, 2023 — Eli Lily’s weight-loss drug retatrutide helped patients lose 24% of their body weight, new data shows. The results rivaled Ozempic. Experts share what to know.
SENIOR-RITA trial investigates the use of an invasive strategy to …
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