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The meaning of SIGNIFICANCE is something that is conveyed as a meaning often obscurely or indirectly. How to use significance in a sentence. Synonym Discussion of Significance.

significance noun, at significant; monoclonal gammopathy of unknown significance; monoclonal gammopathy of undetermined significance, at monoclonal gammopathy of unknown …

The significance of something is the importance that it has, usually because it will have an effect on a situation or shows something about a situation.

Significance definition: importance; consequence.. See examples of SIGNIFICANCE used in a sentence.

Definition of significance noun from the Oxford Advanced Learner's Dictionary. the importance of something, especially when this has an effect on what happens in the future. The new drug …