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Recently improved methods for visualization of thin tissue sections by electron microscopy have been applied to the study of early changes in the bronchial epithelium of mice infected by …

Electron microscopy of resin-embedded samples has traditionally been employed to investigate viral replication in cells. However, this technique relies on chemical fixation of samples, …

Transmission electron microscopy is an imaging technique that visualizes the ultrastructure of samples, revealing not just the structures of interest but also the context occurring around the …

Some properties of influenza virus filaments shown by electron microscopic particle counts. J Gen Microbiol. 1954 Oct;11(2):325–331. doi: 10.1099/00221287-11-2-325. [ DOI ] [ PubMed ] [ …

Aug 20, 1985 · An electron microscopical study was made of the influenza virus, type B/Hong Kong, in the unstained, frozen, hydrated state after quench-freezing in cooled liquid ethane. …

Feb 10, 2025 · Influenza A virus particles strategically adapt their shape – to become either spheres or larger filaments – to favor their ability to infect cells depending on environmental …

Electron micrographs of stain-penetrated influenza virus particles show a variety of internal structures that all consist of units of 4 X 4 nm. Isolated influenza virus M-protein, that is …

Jan 14, 2025 · Colorized negative-stained transmission electron microscope image shows ultrastructural details of a number of influenza virus particles. CDC / Dr. F. A. Murphy. …

Briefly, cryo-electron microscopy (cryo-EM) and cryo-electron-tomography (cryo-ET) have shown the structure of influenza virions at neutral pH in close-to-native conditions; thin section EM …

Here we show a basic methodology to visualize incoming and egressing IAV particles by correlative light and electron microscopy (CLEM). We combine fluorescence microscopy of …

Our findings are in consistent with the earlier electron microscopy studies that had identified extracellular virus particles in lung tissue sections from fatal pH1N1 2009 cases, but we could …

The 3D structure of the influenza virus polymerase complex was determined by electron microscopy and image processing of recombinant ribonucleoproteins (RNPs). The RNPs were …

Jan 15, 1994 · A rapidly frozen vitrified aqueous suspension of influenza A virus was observed by high resolution electron cryomicroscopy. The influenza particles were grouped into small …

Some of the first structural views of influenza virus particles and surface glycoprotein spikes were revealed by electron microscopy using the negative staining technique [6,7,60]. This technique …

May 5, 2022 · While cryo-electron tomography (cryoET) can depict the 3D organization of pleomorphic influenza, the low signal-to-noise ratio inherent to cryoET and viral heterogeneity …

Here, we show using electron tomography and image analyses that isolated RNP filaments are not rigid helical structures, but instead display variations in lengths, curvatures, and even …

Electron microscopy (EM) has long been used in the discovery and description of viruses. Organisms smaller than bacteria have been known to exist since the late 19th century ( 11 ), …

However, HA on the influenza virus surface and designed HA nanoparticles were shown to be in the prefusion state by cryo-electron microscopy (28, 45), and in this study, we determined that …

Influenza virus haemagglutinin (HA) is a key protein that mediates viral invasion of host cells and is the primary target of anti-influenza virus-neutralizing antibodies. HA-induced neutralizing …