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Small cell carcinoma - Pathology Outlines
Sep 20, 2022 · Small cell lung cancer is histologically described as small round / oval cells with high nuclear to cytoplasmic ratio. The nuclei have finely dispersed or salt and pepper chromatin and absent nucleoli. Small cell lung cancer is most often located at the hilum and grows along …
Lung - Pathology Outlines - Biopsies
Nov 25, 2022 · Terminology for small biopsies and cytology versus resection specimens for small cell carcinoma, large cell neuroendocrine carcinoma, adenosquamous carcinoma and …
Pathology Outlines - Malignant
Jun 13, 2024 · Fine needle aspiration of a central lung mass in a patient with an extensive smoking history is diagnosed as small cell lung carcinoma. What feature likely aided this …
Pathology Outlines - Histology
Sep 16, 2021 · Lung histology: basic microscopic structures of the unaffected lung (i.e. nonneoplastic, noninflammatory and nondegenerated lung tissue) Essential features Bronchus …
Pathology Outlines - Staging
Jan 3, 2019 · T, N and M categories code the anatomic extent of lung cancer and predict overall survival of patients with non small cell and small cell carcinomas
Pathology Outlines - WHO classification
Jan 20, 2020 · Being exceptionally rare in the lung, it was introduced in the 2015 WHO classification of lung tumors. Adenosquamous carcinoma and MALT lymphoma are in the …
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Pathology Outlines - SMARCA4 / BRG1
Dec 8, 2022 · In small cell carcinoma of the ovary, whole exome sequencing demonstrated: Frequent loss of heterozygosity at chromosome 19, the location of SMARCA4; Some cases …
Atypical carcinoid tumor / neuroendocrine tumor, grade 2
Dec 9, 2020 · Mostly useful to differentiate lung carcinoids from high grade neuroendocrine carcinomas, in particular in small biopsies or cytology samples (Arch Pathol Lab Med …
Pathology Outlines - Adenocarcinoma overview
Feb 27, 2023 · Adenocarcinoma is a non-small cell lung carcinoma with glandular differentiation, mucin production or pneumocyte marker expression
Lung - Pathology Outlines - Cytology
Sep 1, 2012 · False negatives: often due to sampling (Diagn Cytopathol 2012;40:556); pleural fluid cytology is often falsely negative for small cell carcinoma Also useful for mutation analysis ( …
Pathology Outlines - Squamous cell carcinoma
Aug 8, 2023 · Wide range of nonspecific pulmonary symptoms reported including cough, chest pain, shortness of breath, hemoptysis, wheezing, weight loss, recurrent infections, loss of …
Pathology Outlines - TTF1
Lung small cell carcinoma Positive staining - normal In developing lung starting at 11 weeks of gestation and in adult lung in type II pneumocytes and club cells (formerly Clara cells) ( Mod …
Pathology Outlines - Ki67
2 days ago · High Ki67 proliferative index used as an adverse prognostic marker for breast cancer, bladder cancer, prostate cancer, chordoma Microscopic (histologic) description …
Pathology Outlines - Desmoplastic small round cell tumor
Oct 8, 2021 · Desmoplastic small round cell tumor (DSRCT) is a malignant mesenchymal neoplasm composed of small round tumor cells associated with prominent stromal …
Pathology Outlines - Pulmonary hamartoma
Sep 29, 2022 · Lung, left, needle core biopsy: Pulmonary hamartoma (see comment) Comment: The histologic sections reveal the presence of a benign pulmonary lesion composed of hyaline …
Pathology Outlines - BerEP4 / EpCAM
Dec 12, 2024 · Antibody to cell membrane glycoproteins expressed on healthy epithelia and in various carcinomas Also known as epithelial cell adhesion molecule, BerEp4 (Ber-EP4, J Clin …
Pathology Outlines - Lymphoepithelioma-like
Jan 1, 2018 · Better prognosis than other non small cell carcinomas of lung (Cancer 2012;118:4748, Ann Thorac Surg 2014;98:1013)
Pathology Outlines - NUT carcinoma
Jan 23, 2023 · Small cell carcinoma: Occasional positivity for synaptophysin and nuclear molding in NUT carcinoma is a diagnostic pitfall ( J Thorac Oncol 2015;10:951 ) NUT …
Pathology Outlines - Squamous cell carcinoma in situ
Jun 3, 2024 · Squamous cell carcinoma in situ (SCIS) is a preinvasive lesion originating from the bronchial epithelium and represents a precursor of squamous cell carcinoma (SCC)
Pathology Outlines - Adenosquamous
Mar 1, 2017 · WHO classification as non-small cell lung carcinoma with at least 10% components of both adenocarcinoma and squamous cell carcinoma by histomorphology Diagnosis made …
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