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Aug 2, 2024 · Previous studies have shown that simultaneous knockdown of SLAMF8 and SLAMF9 can prevent endotoxin-induced liver inflammation by suppressing TLR4 expression in …

Signalling lymphocyte activation molecule family member 9 (SLAMF9) is an orphan receptor of the CD2/SLAM family of leucocyte surface proteins. Examination of SLAMF9 expression and …

Sep 19, 2018 · In macrophages SLAMF9 influences TNF-α secretion upon pro-inflammatory stimulation and reduces cell migration. a Transgenic SLAMF9 + U937 cells and EV U937 cells …

Dec 14, 2018 · Here, we show that SLAMF8 and SLAMF9 co-regulate macrophage-mediated liver inflammation. To overcome the redundancy, we generated mice that simultaneously lacked …

In macrophages, SLAMF9 is a novel type-I transmembrane receptor with immunomodulatory characteristics. SLAMF9 affects pro-inflammatory cytokine production and migration in murine …

The presence of SLAMF9+ tumor-associated macrophages (TAMs) in 73.3% of human melanomas. Notably, these macrophages were evident in 95.5% of nevi from melanoma …

Aug 2, 2024 · Overall, SLAMF9 exhibited a positive correlation with immune infiltrating levels of various components, including cancer-associated fibroblasts (CAFs), macrophages, myeloid …

Sep 19, 2018 · Expression of Slamf9, a member of the signaling lymphocytic-activating molecule (Slam) immunoreceptor family, was found to be upregulated in a gene expression analysis of …

Oct 16, 2024 · We identify a group of monocyte-derived Slamf9 + macrophages, which are induced after SARS-CoV-2 infection and resistant to impairment caused by SARS-CoV-2. …

SLAMF9 is a novel type-I-transmembrane receptor with immunomodulatory properties in macrophages. Further studies are required to evaluate whether SLAMF9 classifies as a …

Dec 14, 2018 · We demonstrate that SLAMF8 and SLAMF9 co-regulate macrophage-mediated liver inflammation by maintaining TLR4 expression following LPS exposure, which suggests …

Feb 22, 2021 · Functional studies of SLAMF9 revealed its roles in limiting macrophage migration, mediating plasmacytoid development and activation, positively regulating pathogenic and …

Our study identified SLAMF9 (which belongs to the conserved lymphocytic activation molecule family) as a plasmacytoid dendritic cell receptor that can regulate the function and …

Jul 25, 2019 · Overexpression of SLAMF9 in a murine macrophage cell line resulted in attenuated migration following LPS stimulation, whereas no significant change in TNF-α levels was …

Oct 16, 2024 · We identify a group of monocyte-derived Slamf9+ macrophages, which are induced after SARS-CoV-2 infection and resistant to impairment caused by SARS-CoV-2. Slamf9+ …

Dec 14, 2020 · Here, we show that SLAMF8 and SLAMF9 co-regulate macrophage-mediated liver inflammation. To overcome the redundancy, we generated mice that simultaneously lacked …

May 3, 2022 · After viral clearance, the Slamf9+Spp1+ macrophages differentiated into Trem2+ and Fbp1+ macrophages, both responsible for inflammation resolution and replenishment of …

Signalling lymphocyte activation molecule family member 9 (SLAMF9) is an orphan receptor of the CD2/SLAM family of leucocyte surface proteins. Examination of SLAMF9 expression and …