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Pathology Outlines - Small cell carcinoma
Dec 16, 2022 · Small cell lung cancer is histologically described as small round / oval cells with high nuclear to cytoplasmic ratio. The nuclei have finely dispersed or salt and pepper …
Pathology Outlines - Biopsies
6 days ago · Terminology for small biopsies and cytology versus resection specimens for small cell carcinoma, large cell neuroendocrine carcinoma, adenosquamous carcinoma and …
Pathology Outlines - Malignant
Jun 13, 2024 · Fine needle aspiration of a central lung mass in a patient with an extensive smoking history is diagnosed as small cell lung carcinoma. What feature likely aided this …
Lung - Pathology Outlines - Staging
Jan 3, 2019 · T, N and M categories code the anatomic extent of lung cancer and predict overall survival of patients with non small cell and small cell carcinomas
Pathology Outlines - WHO classification
Jan 20, 2020 · NUT carcinoma. NUT midline carcinoma is a recently recognized highly aggressive tumor defined by a NUT fusion. Being exceptionally rare in the lung, it was introduced in the …
Pathology Outlines - Lung
Interstitial lung diseases associated with smoking: desquamative interstitial pneumonitis respiratory bronchiolitis vaping associated acute lung injury. ... grade 2 large cell …
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Typical carcinoid tumor / neuroendocrine tumor, grade 1
Apr 28, 2023 · Typical carcinoids are not related to smoking (B). The diagnostic criteria of carcinoid tumors of the lung differ from the ones of well differentiated neuroendocrine tumors …
Pathology Outlines - Cytokeratin 20 (CK20, K20)
To distinguish primary lung carcinoma (CK7+ / CK20-) from metastatic colonic carcinoma to lung (CK7- / CK20+, BMC Cancer 2006;6:31) To help distinguish colon carcinoma (80% are CK20+) and poorly differentiated prostatic …
Pathology Outlines - KRAS
Apr 1, 2022 · In non small cell lung cancers (NSCLC), KRAS mutations are common oncogenic drivers and generally exclusive of other driver mutations in genes such as EGFR, ALK and …
Pathology Outlines - Mucoepidermoid carcinoma
May 1, 2018 · Distinguished from other lung cancers by central or peribronchial location, mucous cells, lack of keratinization, expression of p63 and MAML2 rearrangement (Mod Pathol …
Pathology Outlines - Metastases
Jun 1, 2006 · Nodal metastases are common with carcinoma, melanoma or germ cell tumors; rare with CNS tumors and sarcoma (except for angiosarcoma, clear cell sarcoma, epithelioid …
Pathology Outlines - Squamous cell carcinoma
Aug 8, 2023 · Wide range of nonspecific pulmonary symptoms reported including cough, chest pain, shortness of breath, hemoptysis, wheezing, weight loss, recurrent infections, loss of …
Pathology Outlines - Squamous cell carcinoma in situ
Jun 3, 2024 · Squamous cell carcinoma in situ (SCIS) is a preinvasive lesion originating from the bronchial epithelium and represents a precursor of squamous cell carcinoma (SCC)
Pathology Outlines - CEA / CD66e
May 30, 2023 · Pure small cell lung cancer (SCLC) versus small cell lung cancer combined with other pathology (CSCLC): preoperative serum CEA > 6 ng/mL found more frequently in …
Pathology Outlines - Pulmonary hamartoma
Nov 5, 2021 · Lung, left, needle core biopsy: Pulmonary hamartoma (see comment) Comment: The histologic sections reveal the presence of a benign pulmonary lesion composed of hyaline …
Pathology Outlines - Desmoplastic small round cell tumor
Oct 8, 2021 · Desmoplastic small round cell tumor (DSRCT) is a malignant mesenchymal neoplasm composed of small round tumor cells associated with prominent stromal …
Small cell carcinoma of ovary, hypercalcemic type
Jul 26, 2023 · Small cell carcinoma of ovary, hypercalcemic type is a rare and highly aggressive ovarian malignancy defined by an inactivating mutation of the SMARCA4 gene, that occurs in …
Pathology Outlines - CD99
3 days ago · CD99 is a transmembrane protein with various functions and limited diagnostic utility in the differential diagnosis of small round blue cell tumors
Pathology Outlines - PDL1 22C3
Feb 2, 2023 · Current companion diagnostic indications for PDL1 (22C3) include non-small cell lung carcinoma (NSCLC), cervical carcinoma (including cervical squamous cell carcinoma and …
Intrahepatic cholangiocarcinoma (small and large duct types)
Aug 23, 2021 · Small duct type iCCA: peripheral, larger liver masses; shares risk factors with hepatocellular carcinomas (viral hepatitis, nonbiliary cirrhosis) Terminology Also known as …
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