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- Intestinal stem cells are responsible for the remarkable ability of the intestinal epithelium to efficiently renew and repair itself throughout life. The intestinal stem cells reside within specialized instructive niches at the crypt base. WNT is an essential niche factor supplied by both Paneth cells and non-epithelial cells.
www.nature.com/articles/nrm3721 - People also ask
WEBAug 8, 2022 · Abstract. Intestinal stem cells (ISCs) play an important role in maintaining intestinal homeostasis via promoting a healthy gut barrier. Within the stem cell niche, gut microbiota linking the crosstalk of dietary influence and host response has been …
- DOI: 10.7150/ijbs.72600
- Published: 2022
- Publication: Int J Biol Sci. 2022; 18(13): 5185-5206.
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Intestinal stem cells (ISCs) play an important role in maintaining intestinal …
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Intestinal stem cells (ISCs) play an important role in maintaining intestinal …
WEBMar 1, 2024 · Intestinal stem cells (ISCs) are central to the continuous regeneration of this essential tissue 3, 4, 5. ISCs play a pivotal role in maintaining the structural integrity and …
- Studies of stem cells in intestinal homeostasis
WEBDec 11, 2013 · Intestinal stem cells are responsible for the remarkable ability of the intestinal epithelium to efficiently renew and repair itself …
- Author: Nick Barker
- Email: [email protected]
- Publish Year: 2014
WEBThe homeostatic constant regeneration of the intestinal epithelium is driven by active Lgr5 + stem cells (active intestinal stem cells [ISCs]) at the crypt bases, which give rise to …
WEBNutritional Control of Intestinal Stem Cells in Homeostasis and Tumorigenesis. Highlights. Recent interest in dietary research and its impact on ISCs and diseases such as cancer has necessitated an …
WEBJan 18, 2019 · Appropriate control of ISCs and other populations of intestinal epithelial cells with stem cell activity is essential for intestinal homeostasis and regeneration …
WEBReserve Stem Cells in Intestinal Homeostasis and Injury. Renewal of the intestinal epithelium occurs approximately every week and requires a careful balance between cell proliferation and differentiation to maintain …
WEBJun 15, 2011 · Under physiological conditions, intestinal homeostasis is a carefully balanced and efficient interplay between stem cells, their progeny and the …
WEBIntestinal stem cells: guardians of homeostasis in health and aging amid environmental challenges. Exp Mol Med. 2024 Mar 1. doi: 10.1038/s12276-024-01179-1. Online ahead …
WEBMar 1, 2024 · Intestinal stem cells: guardians of homeostasis in health and aging amid environmental challenges - PMC. Journal List. Exp Mol Med. v.56 (3); 2024 Mar. …
The Intestinal Stem Cell Niche: Homeostasis and Adaptations
WEBSep 5, 2020 · Abstract. The intestinal epithelium is a rapidly renewing cellular compartment. This constant regeneration is a hallmark of intestinal homeostasis and …
Cellular Plasticity in Intestinal Homeostasis and Disease - Cell Press
WEBstem cell. plasticity. colorectal cancer. metastasis. Wnt signaling. regeneration. Main Text. Key Definitions. Throughout our review, we will refer to plasticity as the ability of …
Intestinal stem cells and their niches in homeostasis and disease
WEBSep 1, 2023 · 1. Introduction. The function of the intestine includes food digestion, nutrient absorption, waste excretion, and immune defense while providing a barrier to the …
Regulation and plasticity of intestinal stem cells during …
WEBOct 15, 2016 · PDF. Versions. Share. Tools. The intestinal epithelium is the fastest renewing tissue in mammals and has a large flexibility to adapt to different types of …
Host-microbiota interaction in intestinal stem cell homeostasis
WEBMay 17, 2024 · Host-microbiota interaction in intestinal stem cell homeostasis. Haiqin Wu. , Chunlong Mu. , Laipeng Xu. , Kaifan Yu. , Le Shen. & Weiyun Zhu. Article: …
Intestinal stem cell dynamics in homeostasis and cancer
WEBFeb 10, 2022 · Intestinal stem cell dynamics in homeostasis and cancer. Highlights. The stem cell niche dictates intestinal stem cell (ISC) functionality during homeostasis …
Host-microbiota interaction in intestinal stem cell homeostasis
WEBMay 17, 2024 · Intestinal stem cells (ISCs) play a pivotal role in gut physiology by governing intestinal epithelium renewal through the precise regulation of proliferation …
WEBIntestinal stem cells: guardians of homeostasis in health and aging amid environmental challenges. Jiahn Choi 1 and Leonard H. Augenlicht1,2. The Author(s) 2024. The …
The Potential Role of Intestinal Stem Cells and Microbiota for the ...
WEB2 days ago · The interaction between gut microbiota and stem cells influences epithelial self-renewal and overall intestinal homeostasis. Novel therapeutic approaches, …
WEB3.3. Microbiota-nutrient interaction in regulation of ISC homeostasis. Dietary nutrients affect microbial distribution and alter microbial metabolism, thereby regulating the …
Subepithelial Stromal Cells: Their Roles and Interactions with ...
WEBMar 17, 2024 · This interplay controls intestinal stem cell (ISC) homeostasis and epithelial differentiation. The activation of Wnt-promoting pathways and inhibition of …
Regulation of intestinal stem cell niche and colon cancer: from …
WEBThe intestine is one of the fastest regenerative tissues in the body, and homeostasis of the tissue requires robust regulations of intra- and inter-cellular signaling. The stem …
Metabolic Regulation of Intestinal Stem Cell Homeostasis
WEBThe balance between self-renewal and differentiation of intestinal stem cells is essential for intestinal epithelial homeostasis, which can be regulated by dietary cues. Recent …
Modulation of stem cell fate in intestinal homeostasis, injury and ...
WEBMay 5, 2023 · The homeostatic repair and regeneration of the intestinal epithelium are governed by the Lgr5 + intestinal stem cells (ISCs) located at the base of crypts, which …
Intestinal Stem Cells Remodel in Response to Acute Notch …
WEBMay 21, 2024 · INTRODUCTION: Intestinal epithelial cells are rapidly renewed throughout life by intestinal stem cells (ISCs). ISC function is regulated by niche factors that …
Clone wars: From molecules to cell competition in intestinal stem …
WEBSep 18, 2022 · In this review, we highlight the mechanisms that regulate stem cell homeostasis in the small intestine, focusing on Wnt signaling and its regulation by …
Molecular mechanisms of aging and anti-aging strategies | Cell ...
WEBMay 24, 2024 · In addition, the stem cell microenvironment (also called “Niche”) plays a crucial role in maintaining and regulating stem cell function and tissue homeostasis . …
Intestinal stem cells and intestinal homeostasis in health and in ...
WEBIntestinal stem cells and intestinal homeostasis in health and in inflammation: A review. Surgery. 2016 May;159 (5):1237-48. doi: 10.1016/j.surg.2016.01.014. Epub 2016 Feb 28. …
Horizontal mitochondrial transfer as a novel bioenergetic tool for ...
WEBMay 24, 2024 · The mitochondrial donation from mesenchymal stromal/stem cells (MSCs) has gained increasing attention in recent years [], suggesting its potential in stem cell …
Wnt/β-catenin signaling within multiple cell types dependent upon
WEB4 days ago · The gut epithelium is subject to constant renewal, a process reliant upon intestinal stem cell (ISC) proliferation that is driven by Wnt/β-catenin signaling. Despite …
Host-microbiota interaction in intestinal stem cell homeostasis
WEBIntestinal stem cells (ISCs) play a pivotal role in gut physiology by governing intestinal epithelium renewal through the precise regulation of proliferation and differentiation.
Viral infection disrupts intestinal homeostasis via Sting ... - Cell …
WEB17 hours ago · Nigg et al. show that enteric viral infection accelerates the onset of age-associated gut pathology in Drosophila by inducing sustained over-proliferation of …
Reduction of specific enterocytes from loss of intestinal LGR4
WEBMay 23, 2024 · Global deficiency of Lgr4 impairs the development of intestine characterized by absence of Lgr5 + /Olfm4 + intestinal stem cells at E16.5, inhibition of …
GFI1B specifies developmental potential of innate lymphoid cell
WEB13 hours ago · GFI1B is essential to maintain homeostasis of bone marrow–derived ILC progenitors. ... Intestinal cells were isolasted as previously described (63, 64). Cells …
Competing Mechanisms in Bacterial Invasion of Human Colon
WEB35 minutes ago · The gastrointestinal tract is inhabited by a vast community of microorganisms, termed the gut microbiota. Large colonies can pose a health threat but …
Author Correction: c-Maf-dependent Treg cell control of intestinal …
WEBMay 23, 2024 · Author Correction: c-Maf-dependent T reg cell control of intestinal T H 17 cells and IgA establishes host–microbiota homeostasis. Christian Neumann 1,2, Jonas …
Comparison of the effect of Sunset yellow on the stomach
WEB1 day ago · Opposing activities of Notch and Wnt signaling regulate 962 konget al. Intestinal stem cells and gut homeostasis. Cell Rep. 2015; 111: 33-42 https: ... Adult …
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