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  1. Takotsubo cardiomyopathy
    Takotsubo cardiomyopathyType of cardiomyopathy
    RecoverySymptomsCausesDiagnosisTreatmentsDoctors
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  2. Takotsubo cardiomyopathy - Overview

    Verified Expert
    Also known as: stress cardiomyopathy, broken heart syndrome, apical ballooning syndrome
    A temporary condition in which there is a sudden enlargement of the heart muscles, usually caused due to extreme emotional or physical stress.
    Condition Highlight
    Urgent medical attention is usually recommended by healthcare providers
    How common is condition?
    Rare (Fewer than 200,000 cases per year in US)
    Is condition treatable?
    Treatable by a medical professional
    Does diagnosis require lab test or imaging?
    Requires lab test or imaging
    Time taken for recovery
    Can last several weeks or months
    Condition Highlight
    Common for ages 50 and older
    Condition Highlight
    More common in females
    Condition Highlight
    Family history may increase likelihood
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    Causes

    Verified Expert

    • The exact cause is unknown. The extreme stress can release hormones, sush as, adrenaline which can cause temporary heart damage. It occurs following an intense physical or emotional event and may include:
    • Grief from unexpected death or illness of a close relative
    • Divorce
    • A surprise party
    • Sporting triumph
    • Domestic abuse
    • Vehicular accident
    • Having to perform publicly
    • Bad news such as a frightening medical diagnosis
    • Financial loss or job loss
    • A major surgery
    • Strong arguments, betrayal
    • Asthma attack
    • Risk factors include:
    • Gender - more common among women
    • Age - more common after 50 years or older
    • Neurological conditions - persons with certain neurological conditions such as head injury, epilepsy are at highr risk
    • Psychiatric conditions - people suffering from anxiety, mood disorders are at higher risk

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    Symptoms

    Verified Expert
    Seek immediate medical attention if you experience symptoms.

    Symptoms may include:

    • Sudden onset of chest pain
    • Shortness of breath
    • Palpitations - faster heart beat
    • Nausea/vomiting

    See more
    What causes takotsubo cardiomyopathy?
    Catecholamine-induced myocyte injury: It has been suggested that the response to catecholamines (such as epinephrine and norepinephrine, released in response to stress) leads to heart muscle dysfunction that contributes to takotsubo cardiomyopathy.
    en.wikipedia.org

    Treatment

    Verified Expert

    Treatment is depends on the symptoms. The patient is monitored for a minimum of 24 hours.

    Medication

    ACE inhibitors: Used to reduce blood pressure.

    Enalapril

    Beta blockers: Used to manage abnormal heart rhythm.

    Propranolol

    Anticoagulants: May be recommended for a short period of time to prevent stroke.

    Warfarin

    See more
    takotsubo cardiomyopathy_en
    Microsoft Start Health

    Diagnosis

    Verified Expert
    One or more of these tests may be recommended by your medical provider.
    For a person to be diagnosed with this disease, he/she must have gone through a stressful event, show abnormalities in heart rhythm, and show no other causes of heart problems.

    Common tests & procedures

    Patient history: Medical history for symptoms of heart disease in the past and recent stressful events.

    Electrocardiogram (ECG or EKG): To record irregularities in the heartbeat.

    Echocardiogram: To look for abnormalities in the shape or size of the heart.

    Blood test: To look for levels of certain enzymes.

    Coronary angiogram: To rule out blockage in the arteries.

    See more
    Source: Focus Medica. For informational purposes only. Consult a medical professional for advice. | Disclaimer: Opinions are from external health professionals and should not be considered as Microsoft's opinion or a substitute for professional help. Consult a health professional for medical advice.
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    Table of Contents
    Overview
    Causes
    Symptoms
    What causes takotsubo cardiomyopathy?
    Treatment
    Health guide
    Diagnosis
     

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  2. Weakening of the left ventricle
    First described in 1990 in Japan, takotsubo cardiomyopathy is a weakening of the left ventricle, the heart's main pumping chamber. The condition is usually the result of severe emotional or physical stress, such as a sudden illness, the loss of a loved one, a serious accident, or a natural disaster such as an earthquake.
    Phone: (877) 649-9457

    Broken-heart syndrome (takotsubo cardiomyopathy) - Harvard He…

    www.health.harvard.edu/heart-health/takotsubo-cardiomyopathy-broken-heart-syndrome
    www.health.harvard.edu/heart-health/takotsubo-cardiomyopathy-broken-heart-s…
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  3. People also ask
    What is takotsubo cardiomyopathy?
    First described in 1990 in Japan, takotsubo cardiomyopathy is a weakening of the left ventricle, the heart's main pumping chamber. The condition is usually the result of severe emotional or physical stress, such as a sudden illness, the loss of a loved one, a serious accident, or a natural disaster such as an earthquake.

    Takotsubo cardiomyopathy (broken-heart syndrome) - Harvard Health

    health.harvard.edu
    What are the complications of cardiomyopathy?

    Dr. Sujith Chunduri

    MBBS · 2 years of exp

    The complications of cardiomyopathy are: Heart failure as your heart can’t pump enough blood. Arrhythmias may also occur. Blood clots may form as there is poor pump from heart that results in block in blood flow to heart and brain. Heart valve problems as cardiomyopathy leads to enlargement of heart resulting in dysfunction of heart valves. Cause backward flow in the valves. Cardiac arrest and sudden death.
    2 more answers
    bing.com
    What causes takotsubo cardiomyopathy?
    Catecholamine-induced myocyte injury: It has been suggested that the response to catecholamines (such as epinephrine and norepinephrine, released in response to stress) leads to heart muscle dysfunction that contributes to takotsubo cardiomyopathy.

    Takotsubo cardiomyopathy - Wikipedia

    en.wikipedia.org
    Is takotsubo cardiomyopathy a sex difference?
    Years of gender-based research have shown that in matters of the heart, sex differences abound. One striking example is the temporary heart condition known as takotsubo cardiomyopathy, also known as broken-heart syndrome. What is broken heart syndrome?

    Takotsubo cardiomyopathy (broken-heart syndrome) - Harvard Health

    health.harvard.edu
    What are the symptoms of takotsubo cardiomyopathy?
    Symptoms: Precordial pain and dyspnoea similar to the findings in the acute coronary syndrome. Takotsubo cardiomyopathy can also occur without symptoms. Triggers: Emotional or physical stress, although it can also occur without any obvious trigger.

    Takotsubo cardiomyopathy – a clinical review - PMC

    pmc.ncbi.nlm.nih.gov
    Does stress (takotsubo) cardiomyopathy explain acute myocardial stunning?
    30. Lyon AR, Rees PS, Prasad S, Poole-Wilson PA, Harding SE. Stress (Takotsubo) cardiomyopathy – a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning.

    Takotsubo syndrome: the broken-heart syndrome - The British Journa…

    bjcardio.co.uk
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  4. Harvard Health
    https://www.health.harvard.edu/heart-health/...

    Broken-heart syndrome (takotsubo cardiomyopathy) - Harvard …

     
  5. AHA/ASA Journals
    https://www.ahajournals.org/doi/full/10.1161/...

    Takotsubo Syndrome: Pathophysiology, Emerging Concepts, and …

  6. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK430798

    Takotsubo Cardiomyopathy - StatPearls - NCBI …

    May 22, 2023 · Takotsubo cardiomyopathy, also known as Gebrochenes-Herz syndrome, transient apical ballooning syndrome, apical ballooning cardiomyopathy, stress-induced cardiomyopathy, stress cardiomyopathy, and …

  7. American College of Cardiology
    https://www.acc.org/.../03/30/12/17/takotsubo-syndrome

    Takotsubo Syndrome - American College of Cardiology

  8. Johns Hopkins Medicine
    https://www.hopkinsmedicine.org/health/conditions...

    Broken Heart Syndrome - Johns Hopkins Medicine

  9. Explore takotsubo cardiomyopathy explained

  10. Wikipedia
    https://en.wikipedia.org/wiki/Takotsubo_cardiomyopathy

    Takotsubo cardiomyopathy - Wikipedia

  11. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK538160

    Pathophysiology of Takotsubo Syndrome - StatPearls

    Mar 6, 2023 · Introduction. Transient left ventricular (LV) apical ballooning syndrome, Takotsubo cardiomyopathy, Takotsubo syndrome (TTS), broken heart syndrome, ampulla cardiomyopathy, or stress-induced cardiomyopathy are …

  12. JACC Journals
    https://www.jacc.org/doi/10.1016/j.jacc.202…

    Pathophysiology of Takotsubo Syndrome: JACC State …

    Feb 1, 2021 · Takotsubo syndrome (TTS) is an acute cardiac syndrome characterized by typical regional wall motion abnormalities that reflect impairment of myocardial contractility that leads to acute heart failure in the absence of …

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  13. nih.gov
    https://pmc.ncbi.nlm.nih.gov/articles/PMC8733363

    Takotsubo Syndrome: A Review of Presentation, Diagnosis and …

  14. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258224

    Takotsubo cardiomyopathy: A comprehensive review - PMC

  15. British Heart Foundation
    https://www.bhf.org.uk/.../takotsubo-cardiomyopathy

    Takotsubo Cardiomyopathy - Broken Heart Syndrome - BHF

  16. The British Journal of Cardiology
    https://bjcardio.co.uk/2021/03/takotsubo-syndrome...

    Takotsubo syndrome: the broken-heart syndrome - The British …

  17. UpToDate
    https://www.uptodate.com/contents/management-and...

    Management and prognosis of stress (takotsubo) cardiomyopathy

  18. nih.gov
    https://pmc.ncbi.nlm.nih.gov/articles/PMC3539553

    Takotsubo cardiomyopathy – a clinical review - PMC

  19. The BMJ
    https://www.bmj.com/content/340/bmj.c1272

    Takotsubo cardiomyopathy - The BMJ

  20. nih.gov
    https://pmc.ncbi.nlm.nih.gov/articles/PMC8822514

    Takotsubo syndrome: the broken-heart syndrome - PMC

  21. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612566

    Takotsubo Syndrome: Pathophysiology, Emerging Concepts and …

  22. The New England Journal of Medicine
    https://www.nejm.org/doi/full/10.1056/NEJMoa1406761

    Clinical Features and Outcomes of Takotsubo (Stress) …

  23. nih.gov
    https://pmc.ncbi.nlm.nih.gov/articles/PMC10886847

    Exploratory Review of the Takotsubo Syndrome and the Possible …

  24. JACC Journals
    https://www.jacc.org/doi/10.1016/j.jacc.2024.06.040

    Unraveling the Mysteries Surrounding Takotsubo Syndrome: …