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  2. Pathophysiology is uncertain; evidence suggests a surge in stress-related hormones contributes to apical ballooning via disruptions in the microvasculature or by myocardial toxicity. Worldwide, 90% of cases occur in post-menopausal women. In Japan, it is more common in men. Men are more likely to develop the syndrome following physical stress.

    Takotsubo Syndrome - American College of Cardiology

    www.acc.org/latest-in-cardiology/ten-points-to-remember/2020/03/30/12/17/takotsubo-syndrome
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    What is the pathophysiology of takotsubo syndrome?The catecholamine hypothesis is perhaps the most widely accepted pathophysiologic mechanism in Takotsubo syndrome. Estrogen provides direct cardioprotective effects, including vasodilation, vascular protection, and effects against atherosclerosis and endothelial dysfunction.

    Pathophysiology of Takotsubo Syndrome - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
    What is takotsubo cardiomyopathy?However, its pathophysiology is not clearly understood. Takotsubo cardiomyopathy (TCM) is a transient wall motion abnormality of the left ventricular (LV) apex accompanied with emotional or physical stress that usually resolves completely. Takotsubo is a Japanese word meaning a pot with a narrow neck and a round bottom used to catch octopuses.

    Takotsubo cardiomyopathy: Pathophysiology, diagnosis and treatment

    ncbi.nlm.nih.gov
    What causes acute myocardial dysfunction in takotsubo syndrome?Excessive release of cardiac neuronal and systemic catecholamines contributes to acute myocardial dysfunction in patients with Takotsubo syndrome, but impaired microvascular perfusion, myocardial inflammation, and electrophysiological derangements contribute to its clinical manifestations.

    Pathophysiology of Takotsubo Syndrome: JACC State-of-the-Art Review

    jacc.org
    Does inflammation play a role in the development of takotsubo syndrome?Inflammation is thought to play a critical role in the development of Takotsubo syndrome. Cardiac magnetic resonance (CMR) imaging has demonstrated myocardial edema, necrosis, and fibrosis in patients with Takotsubo syndrome.

    Pathophysiology of Takotsubo Syndrome - StatPearls - NCBI Bookshelf

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  4. AHA/ASA Journals
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    Takotsubo Syndrome: Pathophysiology, Emerging Concepts, and …

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    • National Center for Biotechnology Information
      https://www.ncbi.nlm.nih.gov/books/NBK538160

      Pathophysiology of Takotsubo Syndrome - StatPearls

      WEBMar 6, 2023 · Some of the mechanisms proposed for the development of Takotsubo syndrome include elevated levels of circulating plasma catecholamines and their metabolites, microvascular dysfunction, …

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      Takotsubo Myocardial Infarction
    • Studies of takotsubo pathophysiology
      National Center for Biotechnology Information
      Pathophysiology of Takotsubo Syndrome
      Transient left ventricular (LV) apical ballooning syndrome, Takotsubo cardiomyopathy, Takotsubo syndrome (TTS), broken heart syndrome, ampulla cardiomyopathy, or stress-induced cardiomyopathy are interchangeable terms and have all been applied to define
      Author: Nauman Khali…
      Published: 2023/03/06
      Affiliations: MedStar …
      National Center for Biotechnology Information
      Takotsubo cardiomyopathy: Pathophysiology, diagnosis and treatment
      In 1990, takotsubo cardiomyopathy (TCM) was first discovered and reported by a Japanese cardiovascular specialist. Since then, this heart disease has gained worldwide acceptance as an independent disease entity. TCM is an important entity that differs
      Author: Kazuo Komam…
      Published: 2014/07/07
      Publication: World J C…
      National Center for Biotechnology Information
      Takotsubo Cardiomyopathy - StatPearls - NCBI Bookshelf
      Takotsubo cardiomyopathy is also known as a transient apical ballooning syndrome, apical ballooning cardiomyopathy, stress-induced cardiomyopathy, stress cardiomyopathy, and Gebrochenes-Herz syndrome, and broken-heart syndrome is a form of non-ischemic
      Author: Sarah A. Ahm…
      Published: 2023/05/22
      Affiliations: Saint Fran…
      PubMed
      Takotsubo Syndrome: Pathophysiology, Emerging Concepts, and Clinical Implications
      Takotsubo syndrome is a condition characterized by acute transient left ventricular systolic dysfunction, which at presentation can be challenging to distinguish from acute myocardial infarction. Although previously thought to be a benign, self-limiting
      Author: Trisha Singh
      Published: 2022/03/29
      Keywords: Takotsubo …
      PubMed
      Pathophysiology of Takotsubo Syndrome
      Originally described by Japanese authors in the 1990s, Takotsubo syndrome (TTS) generally presents as an acute myocardial infarction characterized by severe left ventricular dysfunction. TTS, however, differs from an acute coronary syndrome because
      Author: Francesco Pell…
      Published: 2017/06/13
      Keywords: Takotsubo …
      National Center for Biotechnology Information
      Takotsubo Syndrome: A Review of Presentation, Diagnosis and Management
      Takotsubo Syndrome (TTS) is a condition of transient left ventricular dysfunction that is typically triggered by emotional or physical stress. Since first described in Japan in 1990, it has increasingly been recognised in clinical practice, accounting
      Author: Joseph Assad…
      Published: 2022
      Publication: Clin Med I…
      National Center for Biotechnology Information
      Takotsubo Syndrome: Pathophysiology, Emerging Concepts and Clinical Implications
      Takotsubo syndrome is a condition characterized by acute transient left ventricular systolic dysfunction, which at presentation can be challenging to distinguish from acute myocardial infarction. Although previously thought to be a benign, self-limiting
      Author: Trisha Singh, …
      Published: 2022/03/03
      DOI: 10.1161/CIRCULA…
      National Center for Biotechnology Information
      Epidemiology, pathogenesis, and management of takotsubo syndrome
      Takotsubo syndrome (TS), also known as broken heart syndrome or neurogenic stunned myocardium, is a recently recognized acute cardiac disease entity [1]. The term takotsubo (tako = octopus, tsubo = a pot) was introduced by Sato and Dote in 1990 and
      Author: Shams Y-Hass…
      Published: 2018
      Publication: Clin Auto…
    • JACC Journals
      https://www.jacc.org/doi/10.1016/j.jacc.202…

      Pathophysiology of Takotsubo Syndrome: JACC State …

      WEBFeb 1, 2021 · The pathophysiology of the Takotsubo form of acute heart failure is incompletely understood. Excessive release of cardiac neuronal and systemic catecholamines contributes to acute myocardial …

    • National Center for Biotechnology Information
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110608

      Takotsubo cardiomyopathy: Pathophysiology, diagnosis and …

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    • National Center for Biotechnology Information
      https://www.ncbi.nlm.nih.gov/books/NBK430798

      Takotsubo Cardiomyopathy - StatPearls - NCBI …

      WEBMay 22, 2023 · HHS. USA.gov. Takotsubo cardiomyopathy is also known as a transient apical ballooning syndrome, apical ballooning cardiomyopathy, stress-induced cardiomyopathy, stress …

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    • American College of Cardiology
      https://www.acc.org/.../03/30/12/17/takotsubo-syndrome

      Takotsubo Syndrome - American College of Cardiology

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    • Nature
      https://www.nature.com/articles/nrcardio.2…

      Epidemiology and pathophysiology of Takotsubo …

      WEBApr 7, 2015 · The pathophysiology of Takotsubo syndrome is complex and integrates neuroendocrine physiology, potentially involving the cognitive centres of the brain, and including the...

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      Takotsubo Epidemiology
    • eMedicine
      https://emedicine.medscape.com/article/1513631-

      Takotsubo (Stress) Cardiomyopathy (Broken Heart Syndrome)

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    • PubMed
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      Takotsubo Syndrome: Pathophysiology, Emerging Concepts, and …

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    • Wikipedia
      https://en.wikipedia.org/wiki/Takotsubo_cardiomyopathy

      Takotsubo cardiomyopathy - Wikipedia

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    • Wiley Online Library
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      Pathophysiology of Takotsubo syndrome - Wiley Online Library

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    • AHA/ASA Journals
      https://www.ahajournals.org/doi/abs/10.1161/...

      Takotsubo Syndrome: Pathophysiology, Emerging Concepts, and …

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      Pathophysiology of Takotsubo syndrome - Wiley Online Library

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    • Springer
      https://link.springer.com/article/10.1007/s10741-023-10381-8

      Takotsubo pathophysiology and complications: what we know

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      Pathophysiology of Takotsubo Syndrome - PubMed

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    • Wiley Online Library
      https://onlinelibrary.wiley.com/doi/10.1155/2024/7259200

      Takotsubo Cardiomyopathy and Autoimmune ... - Wiley Online …

    • MDPI
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      JCM | Free Full-Text | Time Course of Left Ventricular Strain

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    • National Center for Biotechnology Information
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733363

      Takotsubo Syndrome: A Review of Presentation, Diagnosis and …

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      Apical Ballooning Syndrome
      Published:2022
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    • National Center for Biotechnology Information
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612566

      Takotsubo Syndrome: Pathophysiology, Emerging Concepts and …

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    • National Center for Biotechnology Information
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      Epidemiology, pathogenesis, and management of takotsubo …

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