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  2. Neurofibromatosis Type 1 (NF1) and Neurofibromatosis Type 2 (NF2) are two distinct genetic conditions1234:
    • NF1 is more common and characterized by brownish cafe-au-lait spots on the skin, tumors called neurofibromas, and bone deformities.
    • NF2 primarily affects the auditory nerves, leading to hearing loss, and can also cause tumors in other nerves.
    • NF1 is caused by a mutation on chromosome 17, while NF2 is caused by a mutation on chromosome 22.
    Learn more:
    Whereas in NF1, the tumors occur in the small nerves of the skin and the large nerves inside your body, in NF2, tumors primarily affect the auditory nerves that connect the ears to the brain and control hearing. NF2 patients can also develop tumors in the nerves of their body.

    Types of Neurofibromatosis | Mount Sin…

    www.mountsinai.org/care/neurology/services/neuro…
    Scientists have classified NF into two distinct types: neurofibromatosis type 1 (NF1) and NF2. NF1, formerly known as von Recklinghausen's NF, is the more common of the types. It occurs in approximately 1 in 4,000 births. NF2, also referred to as bilateral acoustic NF, central NF or vestibular NF, occurs less frequently- 1 in 40,000 births.

    About Neurofibromatosis - National Hum…

    www.genome.gov/Genetic-Disorders/Neurofibroma…
    Both NF1 and NF2 are genetic conditions that affect nerve tissue, but NF1 and NF2 have different symptoms. NF1, far more common than NF2, is characterized by brownish cafe-au-lait spots on the skin and tumors called neurofibromas. NF1 can also cause deformity of bones and has several other manifestations.

    Neurofibromatosis | Johns Hopkins Medi…

    www.hopkinsmedicine.org/health/conditions-and-di…
    NF1 and NF2 occur as a result of defects in different genes. NF1 is caused by a mutation on the neurofibromin gene located on the pericentromeric region of chromosome 17. NF2 is caused by a mutation on chromosome 22.

    Neurofibromatosis (NF1, NF2) - DermNet

    dermnetnz.org/topics/neurofibromatosis
     
  3. WebMD
    https://www.webmd.com/.../neurofibro…

    Neurofibromatosis 1 and 2: Symptoms, Treatments, …

    WEBApr 26, 2022 — Neurofibromatosis is a genetic disorder of the nervous system that causes tumors to form on nerve tissues. Learn about the …

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    • National Center for Biotechnology Information
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198724

      Current Understanding of Neurofibromatosis Type 1, 2, and ...

    • Videos of Neurofibromatosis Type 1 Vs 2

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    • Mayo Clinic
      https://www.mayoclinic.org/diseases-conditions/...

      Neurofibromatosis type 1 - Symptoms and causes - Mayo Clinic

    • Cleveland Clinic
      https://my.clevelandclinic.org/health/diseases/neurofibromatosis

      Neurofibromatosis: What It Is, Symptoms, Types & Treatment

    • weillcornell.org
      https://neurosurgery.weillcornell.org/co…

      Neurofibromatosis (NF1 and NF2) | Neurological …

      WEBLearn about the two types of neurofibromatosis, a genetic disorder that causes skin and brain tumors. NF1 is characterized by café-au-lait spots and neurofibromas, while NF2 affects the eighth cranial nerve and hearing.

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    • National Institute of Neurological Disorders and Stroke
      https://www.ninds.nih.gov/.../neurofibromatosis

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    • National Center for Biotechnology Information
      https://www.ncbi.nlm.nih.gov/books/NBK459329

      Neurofibromatosis - StatPearls - NCBI Bookshelf

      WEBJan 25, 2023 — Neurofibromatosis type 2 (NF2) is a disease characterized by bilateral vestibular schwannomas (VS) and meningiomas. It has an autosomal dominant inheritance pattern. Treatment for …

    • National Center for Biotechnology Information
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    • Johns Hopkins Medicine
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      Neurofibromatosis - Johns Hopkins Medicine

      WEBNeurofibromatosis is a genetic disorder that causes tumors to form along the peripheral nerves. It has three types: NF1, NF2 and schwannomatosis, each with different symptoms and complications. Learn more about the …

    • Mayo Clinic
      https://www.mayoclinic.org/diseases-conditions/...

      Neurofibromatosis type 1 - Diagnosis and treatment - Mayo Clinic

    • Johns Hopkins Medicine
      https://www.hopkinsmedicine.org/healt…

      Neurofibromatosis Type 1 (NF1) - Johns Hopkins …

      WEBNeurofibromatosis type 1 (NF1) is a genetic disorder that can cause brain tumors, skin tumors, bone deformities and other complications. Learn about the diagnosis, genetic testing and treatment options for NF1 at Johns …

    • Johns Hopkins Medicine
      https://www.hopkinsmedicine.org/health/conditions...

      Neurofibromatosis Type 2 (NF2) - Johns Hopkins Medicine

    • NYU Langone Health
      https://nyulangone.org/conditions/neurofibromatosis/types

      Types of Neurofibromatosis - NYU Langone Health

    • Mount Sinai Health System
      https://www.mountsinai.org/.../neurofibromatosis/types

      Types of Neurofibromatosis | Mount Sinai - New York

    • Wikipedia
      https://en.wikipedia.org/wiki/Neurofibromatosis

      Neurofibromatosis - Wikipedia

    • Cleveland Clinic
      https://my.clevelandclinic.org/health/diseases/14422

      Neurofibromatosis Type 1 (NF1) - Cleveland Clinic

    • UpToDate
      https://www.uptodate.com/contents/90123

      Neurofibromatosis type 1 (NF1): Management and prognosis

    • PubMed
      https://pubmed.ncbi.nlm.nih.gov/34072574

      Current Understanding of Neurofibromatosis Type 1, 2, and ...

    • American Journal of Neuroradiology
      https://www.ajnr.org/content/34/12/2250

      Neurofibromatosis: Types 1 and 2 - American Journal of …

    • National Center for Biotechnology Information
      https://www.ncbi.nlm.nih.gov/books/NBK470350

      Neurofibromatosis Type 2 - StatPearls - NCBI Bookshelf

      WEBOct 3, 2022 — Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder characterized by the development of multiple tumors involving the central nervous system (CNS). Bilateral vestibular schwannomas are …

    • NHS
      https://www.nhs.uk/conditions/neurofibromatosis-type-1

      Neurofibromatosis type 1 - NHS

    • AMBOSS
      https://www.amboss.com/us/knowledge/neurocutaneous-syndromes

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    • National Center for Biotechnology Information
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