RdDM is involved in a number of biological processes in the plant, including stress responses, cell-to-cell … See more

This section focuses on the pathways and mechanisms by which RdDM leads to sequence-specific DNA methylation. The pathways presented here were characterized primarily in the model plant Arabidopsi… See more

While all eukaryotes share three RNA polymerases (RNA Pol I, II and III), plants have two additional polymerases, Pol IV and Pol V. Both Pol IV and V share an evolutionary origin, deriving from Pol II. In other eukar… See more

Introducing transgenes into organisms has been a widely used tool in plant genetics research for decades. However, researchers often find that their introduced transgenes are not expressed as strongly as expecte… See more

Since the mechanism underlying the sequence-specificity of RdDM is well known, RdDM can be ‘tricked’ into targeting and silencing endogenous genes in a highly specific manner, which has a number of potential bi… See more