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FamilyAlphasatellitidaeGenomeThe genome is between 1300 and 1400 nucleotides in length and has three conserved features: a hairpin structure, a single open reading frame (ORF) and an adenine rich region.
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Alpha satellite DNA biology: Finding function in the …
Alpha satellite is often thought to be identical across all centromeres of the human karyotype, but in fact, it exhibits several types of variation or polymorphism that illustrate its complexity, distinctive organization within the human genome, and …
α satellite DNA variation and function of the human …
We recently described variation within α satellite DNA that affects centromere function. On human chromosome 17 (HSA17), we showed that size and sequence polymorphisms within primary array D17Z1 are associated with chromosome …
Evolution of alpha satellite - ScienceDirect
Dec 1, 1991 · Alpha satellite is one of the most thoroughly studied repetitive DNA families and is a paradigm for understanding other satellite DNA and multigene families. Alpha satellite …
The evolutionary dynamics of α-satellite - PMC
α-Satellite is a family of tandemly repeated sequences found at all normal human centromeres. In addition to its significance for understanding centromere function, α-satellite is also a model for …
One class of this DNA, alpha satellite, comprises up to 10% of the genome. Alpha satellite is enriched at all human centromere regions and is compe-tent for de novo centromere assembly.
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Structure, organization, and sequence of alpha satellite DNA from …
The centromeric regions of all human chromosomes are characterized by distinct subsets of a diverse tandemly repeated DNA family, alpha satellite. On human chromosome 17, the …
The evolutionary dynamics of alpha-satellite - PubMed
Alpha-satellite is a family of tandemly repeated sequences found at all normal human centromeres. In addition to its significance for understanding centromere function, alpha …
Complete genomic and epigenetic maps of human …
Human centromeres are located within large arrays of tandemly repeated DNA sequences known as alpha satellite (αSat), which often span millions of base pairs on each chromosome.
Centromeres Take Flight: Alpha Satellite and the …
May 1, 1998 · There is ample evidence implicating a role for alpha satellite in centromere function. The first supportive evidence is “guilt by association”; alpha satellite is the only known human DNA that is exclusively localized to the …
Mar 12, 2021 · Alpha satellite, 53 also named alphoid DNA, comprises up to 10% of the human genome and is mostly found 54 tandemly repeated within constitutive heterochromatin at …
Higher-order repeat structure in alpha satellite DNA occurs in …
May 14, 2015 · Alpha satellite DNA (AS) is the most abundant tandem repeat DNA found in the centromeres of simian primates. The AS of humans contains sequences organized into higher …
Evolutionary History of Alpha Satellite DNA Repeats Dispersed …
Oct 20, 2020 · In this study, using a bioinformatics approach, we characterize annotated alpha satellite repeats (ARs) dispersed within euchromatin of the human genome, in particular those …
Genomic variation within alpha satellite DNA influences …
Alpha satellite is a tandemly organized type of repetitive DNA that comprises 5% of the genome and is found at all human centromeres. A defined number of 171-bp monomers are organized …
Alpha satellite DNA biology: finding function in the recesses of the ...
Jul 5, 2018 · This review will describe the genomic and epigenetic features of alpha satellite DNA, discuss recent findings of noncoding transcripts produced from distinct alpha satellite arrays, …
Evolution of alpha satellite - PubMed
Alpha satellite is one of the most thoroughly studied repetitive DNA families and is a paradigm for understanding other satellite DNA and multigene families. Alpha satellite illustrates both intra- …
Alpha Cubesat HomePage
Alpha Cubesat is a light sail-carrying, cube-shaped satellite—and a stepping stone to our nearest star system. With its holograms, tiny ChipSat computers, and low-cost components, Alpha …
Alpha satellite DNA biology: finding function in the recesses of the ...
Sep 8, 2020 · This review will describe the genomic and epigenetic features of alpha satellite DNA, discuss recent findings of noncoding transcripts produced from distinct alpha satellite …
Firefly pressing ahead with Alpha launches from Wallops and …
Jan 28, 2025 · Render of an Alpha rocket lifting off from Esrange. In collaboration with SSC, Firefly is set to become first U.S. company to launch satellites from continental Europe.
Alpha Satellite Insertion Close to an Ancestral Centromeric Region
Alpha satellite, also named alphoid DNA, comprises up to 10% of the human genome and is mostly found tandemly repeated within constitutive heterochromatin at centromeres and …
