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Long non-coding RNAs (long ncRNAs, lncRNA) are a type of RNA, generally defined as transcripts more than 200 nucleotides that are not translated into protein. [2] This arbitrary limit distinguishes long ncRNAs from small non-coding RNAs, such as microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar ...

Jan 3, 2023 · This Consensus Statement addresses the definition, nomenclature and classification of long non-coding RNAs, and provides a shared viewpoint on their features and functions.

Rapid development in genome-wide transcriptional analyses has led to the discovery of a large number of non-coding transcripts, also called long non-coding RNA (lncRNA). LncRNAs harbor biological activities including regulation of protein-coding ...

Dec 22, 2020 · Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs) are widely expressed and have key roles in gene regulation. Recent studies have begun to unravel how the...

Long non-coding (lnc) RNAs are non-coding RNAs longer than 200 nt. lncRNAs primarily interact with mRNA, DNA, protein, and miRNA and consequently regulate gene expression at the epigenetic, transcriptional, post-transcriptional, translational, and post-translational levels in a variety of ways.

Nov 14, 2024 · In celebration of Cell ’s 50th anniversary, this Review explores our current understanding of the most extensively studied regulatory ncRNAs—small RNAs and long non-coding RNAs (lncRNAs)—which have profoundly shaped the field of RNA biology and beyond.

Long non-coding RNAs (ncRNAs) are RNA transcripts of more than 200 nucleotides that do not encode proteins. Long ncRNAs have been implicated in the regulation of gene expression, dosage compensation and imprinting [ 1,2 ].