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  2. Dictionary

    chal·lenge
    [ˈCHalənj]
    noun
    challenge (noun) · challenges (plural noun)
    1. a call to take part in a contest or competition, especially a duel:
      "he accepted the challenge"
      • a task or situation that tests someone's abilities:
        "the ridge is a challenge for experienced climbers"
      • an attempt to win a contest or championship in a sport:
        "a world title challenge"
    2. an objection or query as to the truth of something, often with an implicit demand for proof:
      "a challenge to the legality of the order"
      Similar:
      confrontation with
      dispute with
      stand against
      test of
      disagreement with
      questioning of
      • a sentry's call for a password or other proof of identity:
        "I heard the challenge “Who goes there?”"
      • law
        an objection regarding the eligibility or suitability of a jury member.
    3. medicine
      the administration of an immunogenic or infectious agent to an animal or person, in order to study the resulting immune response or measure the efficacy of a vaccine:
      "challenge trials have yielded positive results when carefully and ethically conducted" · "human challenge studies occur in tightly controlled settings" · "recently vaccinated calves should be protected from challenge"
    verb
    challenge (verb) · challenges (third person present) · challenged (past tense) · challenged (past participle) · challenging (present participle)
    1. invite (someone) to engage in a contest:
      "he challenged one of my men to a duel" · "organizations challenged the government in by-elections"
      Similar:
      throw down the gauntlet to
      defy someone to do something
    2. dispute the truth or validity of:
      "it is possible to challenge the report's assumptions"
      Similar:
      disagree with
      object to
      protest against
      call into question
      demur about/against
      dissent from
      be a dissenter from
      • law
        object to (a jury member).
      • (of a guard) order (someone) to prove their identity:
        "the watchman did not challenge him"
    3. medicine
      administer an immunogenic or infectious agent to an animal or person, in order to study the resulting immune response or measure the efficacy of a vaccine:
      "the mice were challenged with the influenza virus"
    Origin
    Middle English (in the senses ‘accusation’ and ‘accuse’): from Old French chalenge (noun), chalenger (verb), from Latin calumnia ‘calumny’, calumniari ‘calumniate’.
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