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  2. Dictionary
    ir·ri·ta·tion
    [ˌirəˈtāSHən]
    noun
    irritation (noun) · irritations (plural noun)
    1. inflammation or other discomfort in a body part caused by reaction to an irritant substance:
      "some chemicals cause a direct irritation to the skin leading to dermatitis"
      • biology
        the stimulation of an organism, cell, or organ to produce an active response.
    Origin
    late Middle English: from Latin irritatio(n-), from the verb irritare (see irritate).
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