ExCeL London is divided into two main halls, the North and South halls, which are connected by a central boulevard. The expansive layout provides over 100,000 square metres (over 1 million square feet) of flexible exhibition space, divided into multiple halls that can be adapted to suit the scale and requirements of different events.

The design of the exhibition building consists of two column-free, rectangular, sub-divisible halls of approximately 479,493 sq. ft. (44,546 sq. m.), on either side of a central boulevard containing catering facilities and information points. There are also three sets of function rooms, one overlooking the water, another above the western end of the central boulevard, and the third on the north side of the building which are used for smaller meetings, seminars, presentations and corporate hospitality.