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    Major Affective Disorder and Mitral Annulus Disjunction
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    MAD can refer to two different medical terms: Major Affective Disorder and Mitral Annulus Disjunction.
    Major Affective Disorder is a broad category of mental health conditions characterized by persistent and significant disturbances in mood. This category includes major depressive disorder, bipolar disorder, and cyclothymic disorder.
    Mitral Annulus Disjunction (MAD) is a structural abnormality of the heart in the mitral annulus ring. It is generally defined as an abnormal displacement of the location of where the posterior mitral valve leaflet inserts onto the left atrial wall and the left ventricular wall.
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