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  2. Research suggests that Spice and other forms of synthetic cannabis is capable of producing much more intense and prolonged effects at much lower doses than natural cannabis. This is because, while the THC in natural cannabis only partially reacts with the body, synthetic cannabis reacts far more fully.
    www.acsh.org/news/2016/09/25/synthetic-cannabi…
    It's been suggested that some artificial cannabinoid compounds found in Spice act more strongly on, and bind more closely to, the brain's receptors than tetrahydrocannabinol (THC), the chemical responsible for most of the psychological effects of ordinary cannabis.
    www.bbc.co.uk/news/magazine-32827840
    Synthetic drugs like Spice are meant to mimic the effects of another drug (in Spice's case, marijuana0, but they can be much more potent and dangerous. They can cause serious health problems, ranging from anxiety and paranoia to heart palpitations and seizures, and in many cases, these drugs have been associated with fatalities.
    www.theedgetreatment.com/spice-drug-its-usage-a…
    Spice, or synthetic cannabis, is neither natural nor safe. It does contain dried plant materials, but the active ingredients are actually man-made chemicals that are sprayed onto the plants. The resulting substance is very potent and has effects that are up to ten times stronger than natural marijuana.
    drugabuse.com/blog/an-ultimate-guide-to-understa…
     
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  4. WEBSep 23, 2016 · Spice is not a single drug, but a range of laboratory-made chemicals that mimic the effects of tetrahydrocannabinol (THC), the main psychoactive component of cannabis. Research suggests that...

     
  5. Sept 28, 2021: What is “Spice” and Why is it Not Just Marijuana?

  6. Why synthetic marijuana is so risky - The Conversation

  7. What is Spice and Why is the Drug so Dangerous?

  8. Experts issue warning over cannabis sweets laced with Spice - BBC

  9. Synthetic Cannabis: Why Is 'Spice' So Dangerous?

  10. Why “spice” is worse than other drugs - The Economist

  11. Synthetic cannabinoids (Spice) | NHS inform

  12. Synthetic cannabinoids | Effects and Risks | FRANK

  13. Spice: The dangerous alternative to cannabis - BBC News

  14. 'Spice' users likely to experience more severe withdrawal …

  15. Spice: The dangerous alternative to cannabis - BBC News

  16. 'Spice' Or Synthetic Marijuana Linked To Psychosis, Brain, and

  17. Here's Why Synthetic Marijuana Isn't Safe | Live Science

  18. What is Spice and why is the drug so dangerous?

  19. Your Herbs and Spices Might Contain Arsenic, Cadmium, and Lead