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  1. Arthritis is caused by various reasons. The common causes include:

    • Wear and tear of cartilage in joints
    • Metabolic abnormalities- there is imbalance of many chemical substances in the body
    • Infection (Bacterial or Viral)
    • Autoimmune disease- the body mistakenly fights its own cells
    • Injury

    Risk factors include:

    • Family history
    • Obesity
    • Age - increases with age
    • Gender - Women are more likely to develop arthritis

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    Complications

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    If arthritis is left untreated, it can lead to serious complications such as:

    • Joint damage: Joint deformities, damage to nearby tendon, etc
    • Widespread inflammation: Inflammation can spread to other parts of the body like lungs, heart, and eyes
    • Cardiovascular damage: People with rheumatoid arthritis are at higher risk of developing cardio vascular disease

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    Symptoms

    Verified Expert
    Contact your provider if experiencing new, severe, or persistent symptoms.

    Symptoms vary depending on the type of arthritis. The most common symptoms in the initial stages are:

    • Joint pain- knee or hip pain
    • Swelling
    • Redness in the joints
    • Tenderness in joints
    • Loss of appetite
    • Fever

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    Diagnosis

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    One or more of these tests may be recommended by your medical provider.
    Doctors will examine joint movements. Blood test and imaging tests help in diagnosing the severity of inflammation and check the progression of disease.

    Common tests & procedures

    Physical examination: To examine swelling of joints and redness.

    Erythrocyte sedimentation rate (ESR): It is a blood test to check inflammation.

    C-reactive protein (CRP): This is a blood marker test to determine acute inflammation. CRP is produced in liver and the higher level indicates the degree of inflammation.

    Antinuclear antibody test (ANA): A blood test to measure the antibodies that attack the healthy proteins. It helps in diagnosing auto-immune diseases.

    Anti-cyclic citrullinated protein test (Anti-CCP): To identify the anti-CCP antibody, which is an antibody that causes RA.

    X-ray: Knee X-ray is taken to check the cartilage loss, bone damage and bone spurs. X-rays are also used to track the progression of the disease.

    Magnetic resonance imaging (MRI): MRI scan of joints provides more detailed images of cartilage, tendons and ligaments.

    CT scan: CT Scan of the joints helps in checking the bones and the surrounding tissues.

    Ultrasound: Instrumental in checking for any fluid containing structures in joints. This is also used to guide needle placement for injections and joint aspirations.

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    Treatment

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    Treatments vary depending on the type of arthritis. The treatment focuses on reducing symptoms and improving quality of life.

    Medication

    Analgesics: Reduces joint pain but does not reduce the inflammation.

    Acetaminophen

    Nonsteroidal anti-inflammatory drugs (NSAIDs): It will help reduce both pain and inflammation.

    Ibuprofen

    Corticosteroids: Reduce inflammation and suppress the immune system.

    Triamcinolone . Methylprednisolone

    Disease-modifying antirheumatic drugs (DMARDs): The most standard RA treatment helps to slow down the progression of RA.

    Azathioprine . Cyclophosphamide

    Pain killers: It will reduce the joint pain.

    Capsaicin

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  2. Arthritis can be caused by various factors, including123:
    • Wear and tear of the joint over time or overuse (Osteoarthritis)
    • Problems with the immune system attacking the body’s own tissues (Rheumatoid arthritis, lupus, and scleroderma)
    • Genetic factors
    • Infections or injuries to the joints
    • Metabolic conditions (e.g., gout)
    Learn more:
    The cause depends on the type of arthritis. Osteoarthritis is caused by the wear and tear of the joint over time or because of overuse. Rheumatoid arthritis, lupus, and scleroderma are caused by the body’s immune system attacking the body’s own tissues.
    www.hopkinsmedicine.org/health/conditions-and-di…
    The exact cause of many types of arthritis are not fully known. Genetic factors may be involved. Many forms of arthritis are caused by problems with your immune system. Other forms of arthritis, such as gout, are caused by a metabolic condition.
    www.healthdirect.gov.au/arthritis
    Arthritis may be caused by: Normal wear and tear causes OA, one of the most common forms of arthritis. An infection or injury to the joints can exacerbate this natural breakdown of cartilage tissue. Cartilage is a firm but flexible connective tissue in your joints.
    www.healthline.com/health/arthritis
     
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