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  2. Then, in 1906, secretions from the ovaries were shown to produce estrus (cyclic sexual activity in non-human females) and the term “estrogen” was born, derived from the Greek oistros (mad desire) and gennan (to produce). Yet, it was not until 1929 that estrogen as a hormone was isolated.
    www.urmc.rochester.edu/ob-gyn/ur-medicine-meno…
    January 1, 1923 at 6:50 pm Two scientists at Washington University of St. Louis, Edgar Allen and Edward Doisy, first isolated estrogen in experimental mice and found that it was produced in the ovaries.
    www.sciencenews.org/century/milestone/estrogen …
     
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    Estrogen - Wikipedia

    In 1929, Adolf Butenandt and Edward Adelbert Doisy independently isolated and purified estrone, the first estrogen to be discovered. Then, estriol and estradiol were discovered in 1930 and 1933, respectively. Shortly following their discovery, estrogens, both natural and synthetic, were introduced for … See more

    Estrogen (British English: oestrogen; see spelling differences) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major See more

    Biochemistry image

    Estrogens are used as medications, mainly in hormonal contraception, hormone replacement therapy, and to treat gender dysphoria in transgender women and other transfeminine individuals as part of feminizing hormone therapy. See more

    Etymology
    The name estrogen is derived from the Greek οἶστρος (oîstros), literally meaning "verve" or "inspiration" but figuratively sexual passion or … See more

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    Biological function image

    The four major naturally occurring estrogens in women are estrone (E1), estradiol (E2), estriol (E3), and estetrol (E4). Estradiol (E2) is … See more

    The actions of estrogen are mediated by the estrogen receptor (ER), a dimeric nuclear protein that binds to DNA and controls gene expression. Like other steroid hormones, … See more

    Biosynthesis
    Estrogens, in females, are produced primarily by the ovaries, and during pregnancy, the See more

    The estrogen steroid hormones are estrane steroids. See more

     
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  5. History of Estrogen: Its Purification, Structure, Synthesis, Biologic ...

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  7. The History of Estrogen - February 2016 - University …

    Feb 17, 2016 · The first commercial preparation of estrogen began as an estrogen complex extracted from placentas called Emmenin, which was used to treat dysmenorrhea. The pharmaceutical company Ayerst, McKennen, and …

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    Sep 6, 2023 · For people assigned female at birth, the role of estrogen goes beyond fertility and sex-related functions. It includes protective effects on mood and mental health, bone strength, and even heart health. Estrogen also may …

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