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Aromatase - Wikipedia
Aromatase (EC 1.14.14.14), also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP19A1 , a member of the …
Aromatase Inhibitors: Uses, Dosage, Side Effects, Interactions
Jan 26, 2023 · Aromatase inhibitors are drugs used to prevent cancer recurrence in women with estrogen-sensitive breast cancer. Learn about dosages and side effects.
Aromatase Inhibitors: Benefits, Side Effects, and More - Breastcancer.org
Learn more about aromatase inhibitors, including the three types, why they’re used in breast cancer treatment, their side effects, and their benefits.
Aromatase - an overview | ScienceDirect Topics
Aromatase is the rate-limiting enzyme in the biosynthesis of estrogens, which play crucial roles on a spectrum of developmental and physiological processes. The biological actions of estrogens …
Tissue Physiology and Pathology of Aromatase - PMC
Aromatase is expressed in multiple tissues, indicating a crucial role for locally produced oestrogens in the differentiation, regulation and normal function of several organs and …
Breast Cancer Prevention: Aromatase Inhibitors
Aromatase inhibitors (AIs) are drugs used to lower breast cancer risk in some post-menopausal women. For post-menopausal women with a higher-than-average risk of breast cancer, these …
Aromatase Inhibitors - StatPearls - NCBI Bookshelf
Jul 4, 2023 · Aromatase inhibitors decrease estrogen by inhibiting the conversion of testosterone to estrogen and have therefore been used in patients with short stature and/or constitutional …
Biology of Aromatase - Holland-Frei Cancer Medicine - NCBI …
Aromatase catalyzes three separate steroid hydroxylations involved in the conversion of androstenedione to estrone. The first two give rise to 19-hydroxy and 19-aldehyde structures, …
Aromatase in the Human Brain - PMC - PubMed Central (PMC)
The aromatase cytochrome P450 (P450arom) enzyme, or estrogen synthase, which is coded by the CYP19A1 gene, is widely expressed in a subpopulation of excitatory and inhibitory …
Structural and Functional Characterization of Aromatase, …
Aromatase is an enzyme that converts androgens into estrogens, and aromatase inhibitors (AIs) can eliminate the production of estrogen. Furthermore, antiestrogens can bind to ER and …
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