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Aromatase (EC 1.14.14.14), also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP19A1 , a member of the …

Jan 26, 2023 · Aromatase inhibitors are drugs used to prevent cancer recurrence in women with estrogen-sensitive breast cancer. Learn about dosages and side effects.

Learn more about aromatase inhibitors, including the three types, why they’re used in breast cancer treatment, their side effects, and their benefits.

Aromatase is the rate-limiting enzyme in the biosynthesis of estrogens, which play crucial roles on a spectrum of developmental and physiological processes. The biological actions of estrogens …

Aromatase is expressed in multiple tissues, indicating a crucial role for locally produced oestrogens in the differentiation, regulation and normal function of several organs and …

Aromatase inhibitors (AIs) are drugs used to lower breast cancer risk in some post-menopausal women. For post-menopausal women with a higher-than-average risk of breast cancer, these …

Jul 4, 2023 · Aromatase inhibitors decrease estrogen by inhibiting the conversion of testosterone to estrogen and have therefore been used in patients with short stature and/or constitutional …

Aromatase catalyzes three separate steroid hydroxylations involved in the conversion of androstenedione to estrone. The first two give rise to 19-hydroxy and 19-aldehyde structures, …

The aromatase cytochrome P450 (P450arom) enzyme, or estrogen synthase, which is coded by the CYP19A1 gene, is widely expressed in a subpopulation of excitatory and inhibitory …

Aromatase is an enzyme that converts androgens into estrogens, and aromatase inhibitors (AIs) can eliminate the production of estrogen. Furthermore, antiestrogens can bind to ER and …