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- Common brand names: Nolvadex, Soltamox
Tamoxifen is used to treat breast cancer. It is also used to reduce the chances of breast cancer in high-risk patients.
May Treat: Breast cancer in high risk women · Ductal carcinoma in situ of breast · Hormone receptor positive breast cancer
Brand Names: Nolvadex · Soltamox
Drug Class: Antineoplastic - Selective Estrogen Receptor Modulators (SERMs)
Availability: Prescription Required
Pregnancy: Consult your doctor. This medication may be harmful to an unborn child.
Lactation: This drug should not be given to breastfeeding mothers
PrecautionsFor informational purposes only. Consult a medical professional for advice.
Source: First Databank Learn more
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See all on WikipediaTamoxifen - Wikipedia
Tamoxifen is a nonsteroidal SERM of the triphenylethylene family and was structurally derived from diethylstilbestrol-like estrogens and antiestrogens such as chlorotrianisene and ethamoxytriphetol. Initially, clomifene was synthesized, and tamoxifen was developed subsequently. Tamoxifen is closely … See more
Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men. It is also being studied for other types of cancer. … See more
A report in September 2009 from Health and Human Services' Agency for Healthcare Research and Quality suggests that … See more
Dysmenorrhea
Tamoxifen has been used effectively to improve blood flow, reduce uterine contractility and pain in See moreTamoxifen has a number of contraindications, including known hypersensitivity to tamoxifen or other ingredients, individuals taking concomitant coumarin-type anticoagulant therapy, and women with a history of venous thromboembolism See more
Acute overdose of tamoxifen has not been reported in humans. In dose-ranging studies, tamoxifen was administered at very high doses in women (e.g., 300 mg/m ) and was found to produce acute neurotoxicity including tremor, hyperreflexia See more
Pharmacodynamics
Selective estrogen receptor modulator activity
Tamoxifen acts as a See moreWikipedia text under CC-BY-SA license Tamoxifen: a most unlikely pioneering medicine - Nature
WEBTamoxifen, an agent kept on life support for the first 20 years of its existence (1962–1982), evolved into the first targeted medicine for breast cancer.
- Studies of who makes tamoxifen
Tamoxifen – the start of something big - Cancer …
WEBOct 15, 2012 · ICI46,474 – as tamoxifen was known back then – was first made in 1966 by scientists working for Imperial Chemical Industries Pharmaceuticals (ICI, now AstraZeneca), who had been tasked with …
Tamoxifen from Failed Contraceptive Pill to Best-Selling Breast …
WEBSep 12, 2017 · Introduction. Today, tamoxifen (brand name Nolvadex) is one of the world's best-selling hormonal breast cancer drugs. However, it was not always so.
Tamoxifen: What to Expect, Side Effects, and More
WEBTamoxifen blocks cancer cells from being able to use estrogen to grow. You may be prescribed tamoxifen if you have been diagnosed with hormone receptor-positive breast …
Tamoxifen evolution - PMC - National Center for Biotechnology …
WEBFeb 2, 2023 · Trimethylphenylethylene (M260) formed the basis of the development of tamoxifen in the 1960s. The lead compound for tamoxifen development was found to be …
Tamoxifen | Breast Cancer Treatment, Hormone Therapy & Side …
WEBAug 6, 2024 · anticancer drug. tamoxifen, synthetic hormone, used primarily in the prevention and treatment of breast cancer, that inhibits the growth-promoting actions of …
Tamoxifen - Memorial Sloan Kettering Cancer Center
WEBDec 12, 2022 · Brand Names: US. Soltamox. Brand Names: Canada. APO-Tamox; Nolvadex D [DSC]; TEVA-Tamoxifen. Warning. This drug may raise the chance of very …
Tamoxifen for Breast Cancer Treatment, Prevention - WebMD
WEBApr 22, 2022 · Breast Cancer Guide. Tamoxifen for Breast Cancer Treatment, Prevention. Medically Reviewed by Dany Paul Baby, MD on April 22, 2022. Written by Debra …
Tamoxifen evolution | British Journal of Cancer - Nature
WEBFeb 10, 2023 · Trimethylphenylethylene (M260) formed the basis of the development of tamoxifen in the 1960s. The lead compound for tamoxifen development was found to be …
Breast cancer chemoprevention: Drugs that reduce risk
WEBOct 28, 2023 · Tamoxifen blocks the effects of estrogen — a reproductive hormone that influences the growth and development of many breast cancers. Tamoxifen belongs to …
Long-Term Data from 20 Trials Confirm Tamoxifen's Long-Lasting …
WEBAug 27, 2011 · The main drugs used in adjuvant hormone therapy for women with early-stage ER-positive breast cancer are tamoxifen and the aromatase inhibitors …
Tamoxifen CITRATE - Uses, Side Effects, and More - WebMD
WEBCommon Brand (S): Soltamox , nolvadex. Generic Name (S): tamoxifen. Uses. Side Effects. Warnings. Precautions. Interactions. Uses. Tamoxifen is used to treat breast …
Tamoxifen Uses, Dosage, Side Effects - Drugs.com
WEBJul 29, 2024 · Medically reviewed by Sophia Entringer, PharmD. Last updated on Jul 29, 2024. Uses. Warnings. Before taking. Side effects. Dosage. Interactions. FAQ. What is …
Five Years of Tamoxifen Continues to Benefit Women 15 Years …
WEBMar 21, 2011 · The drug tamoxifen, a type of hormone therapy, is a standard treatment for women with estrogen receptor-positive breast cancer. A 2005 meta-analysis ( see the …
The Truth about Tamoxifen - CANCERactive
WEBJul 27, 2018 · Tamoxifen is sold under the brand names of Nolvadex, Soltamox and Tamofen amongst others. It was originally developed by chemist Dora Richardson in …
Tamoxifen a pioneering drug: An update on the ... - ScienceDirect
WEBJan 1, 2018 · Tamoxifen (ICI 46 474), trans -1- (4-β-dimethylaminoethoxyphenyl)-1,2-diphenylbut-1-ene, is the most commonly used drug for the treatment of estrogen …
Tamoxifen a pioneering drug: An update on the therapeutic
WEBJan 1, 2018 · Tamoxifen (ICI 46 474), trans-1-(4-β-dimethylaminoethoxyphenyl)-1,2-diphenylbut-1-ene, is the most commonly used drug for the treatment of estrogen …
Tamoxifen for women at high risk of breast cancer - PMC
WEBFeb 17, 2014 · Tamoxifen is an ER antagonist that has been used as a treatment for patients with breast cancer since the early 1970s. 1 A collaborative meta-analysis …
Tamoxifen Citrate - NCI - National Cancer Institute
WEBSoltamox. FDA Approved. Yes. FDA label information for this drug is available at DailyMed. Use in Cancer. Tamoxifen citrate is approved to treat: Breast cancer in women and …
Tamoxifen Patients: Your Treatment, Your Choice - Soltamox®
WEBSOLTAMOX is a prescription medicine used: to treat adults with estrogen receptor-positive breast cancer that has spread to other parts of the body (metastatic) to treat adults with …
Side effects of low-dose tamoxifen: results from a six-armed
WEBMay 6, 2023 · Adherence to adjuvant tamoxifen therapy is suboptimal, and acceptance of tamoxifen for primary prevention is poor. Published results indicate effect of low-dose …
Hormone Therapy for Breast Cancer Fact Sheet - NCI
WEBJul 12, 2022 · For example, tamoxifen blocks the effects of estrogen in breast tissue but acts like estrogen in the uterus and bone. Other antiestrogen drugs, such as fulvestrant …
New drug combinations could improve therapies for breast …
WEB3 days ago · OHSU study finds drug combinations slow progression of the cancer and lead to cancer regression.
Lives & Legacies: Obituaries for August 2024 | McKinsey
WEB1 day ago · Our August 2024 obituaries include a media CEO, a neonatal ICU creator, and a corporate cofounder who helped change the face of word processing.
First Cancer TCR Cell Therapy Approved by FDA - NCI
WEB3 days ago · FDA has approved the first cancer TCR cellular therapy. Tecelra, or afami-cel, is used to treat metastatic synovial sarcoma that’s positive for MAGE-A4.
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