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- In rheumatoid arthritis, a condition known as "Z deformity" may occur in the thumb. This deformity consists of hyperextension of the interphalangeal joint and fixed flexion and subluxation of the metacarpophalangeal joint1. The Z deformity can severely impact thumb function, which is important for opposition and essential for pinches and grips in daily activities2.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.A 'Z deformity' may occur in rheumatoid arthritis. It is seen at the thumb and consists of hyperextension of the interphalangeal joint, and fixed flexion and subluxation of the metacarpophalangeal joint.gpnotebook.com/pages/haematology/z-deformityZ deformity of the thumb prevents pinching because the force of the tendons causes the thumb to collapse into MCP flexion and IP hyperextension. Thumb function is important for opposition, which is essential for pinches and grips. Therefore, this deformity can severely interrupt activities of daily living requiring opposition.www.physio-pedia.com/Biomechanics_of_Hand_a…
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