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- Lialda and Delzicol are both medications used to treat ulcerative colitis (UC)1. They both contain the same active ingredient: mesalamine1. However, they differ in the specific formulation of 5-ASA, how many times per day they are taken, and the way the pills dissolve in particular parts of the bowel2. Asacol HD is another medication that works similarly to Lialda and Delzicol1. Asacol HD, Lialda, and Delzicol are all formulated differently to control where mesalamine is released in your body13.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Asacol HD, Lialda, and Delzicol are medications used to treat ulcerative colitis (UC). They all contain the same active ingredient: mesalamine. These medications work to lessen the inflammation caused by UC, which can help control your symptoms. But they’re all formulated differently to control where mesalamine is released in your body.www.goodrx.com/mesalamine/asacol-vs-lialda-vs-d…Several formulations of the 5-ASA drugs are available (sample brand names: Delzicol, Asacol HD, Pentasa, Dipentum, Colazal, Apriso, and Lialda). These differ in the specific formulation of 5-ASA, how many times per day they are taken, and the way the pills dissolve in particular parts of the bowel.www.uptodate.com/contents/sulfasalazine-and-the …Asacol®, Asacol®HD and Delzicol®tablets contain a pH-sensitive film that dissolves at a higher pH, thereby delivering mesalamine to the terminal ileum and proximal colon. Lialda®and Apriso®are formulated in a matrix that delays mesalamine release until it reaches the distal ileum and colon.www.medicaid.nv.gov/Downloads/provider/Ulcerati…
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