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  3. The retinaldehyde reductase DHRS3 is essential for preventing …

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    Does DHRS3 reduce retinaldehyde?These data demonstrate that the reduction of retinaldehyde by DHRS3 is critical for preventing formation of excess ATRA during embryonic development.—Billings, S. E., Pierzchalski, K., Butler Tjaden, N. E., Pang, X.-Y., Trainor, P. A., Kane, M. A., Moise, A. R.
    Why is DHRS3 important in embryonic development?During embryonic development, which is critically dependent on finely regulated concentrations of RA ( 30 ), DHRS3 was required in the embryo, primarily within the central nervous system ( 12 ), where it apparently functions as an RA-induced feedback inhibitor of RA synthesis and is highly active at the onset of gastrulation ( 17 ).
    Is AMD FSR 3 available in upcoming games?When we launched AMD FSR 3 in September 2023, it was available in two games, Forspoken and Immortals of Aveum™, with an additional 10 games announced as upcoming titles. Now, six months later, we have an incredible 40 available and upcoming games with support for FSR 3.
  5. DHRS3, a retinal reductase, is differentially regulated by retinoic ...

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