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  2. Tyrer-Cuzick model

    The Tyrer-Cuzick model, sometimes referred to as IBIS tool, provides a risk score that estimates the likelihood of a woman developing breast cancer in 10 years and over the course of her lifetime. The risk score is calculated using a variety of risk factors that include personal health history, as well as family history of cancers.
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    What is the Ibis model?The IBIS model, also known as the Tyrer-Cuzick model, is also a widely used breast cancer risk prediction model, which takes into account multigenerational family history data and mutation information.
    Do ibis 10-year risk estimates overestimate breast cancer risk?In this study, we found that IBIS 10-year risk estimates overestimated risk of breast cancer in this high-risk population of women. Furthermore, we found that using age-specific risk thresholds for risk stratification will likely optimize a risk-stratified approach to screening for this population.
    Does the Ibis model perform better?In summary, we found that the IBIS model performed better in this cohort whose risks span the continuum of breast cancer risk. This was true even in subgroups containing women typically considered average risk (for example, no family history of breast cancer, BRCA1/2 mutation negative).
    What are the results based on the Ibis risk assessment model?The results below are based on the IBIS risk assessment model. These results display your 10-year risk and your lifetime risk compared to the U.S. population average. Please consult with your physician should you have any questions about your risk for breast cancer or for guidance on options for breast cancer screening or genetic counseling.
     
  4. Ikonopedia IBIS: Online Tyrer-Cuzick Model Breast Cancer Risk ...

     
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    WEBJul 6, 2021 · The IBIS/Tyrer-Cuzick model is well calibrated for several racial/ethnic groups over 2 decades of follow-up. Studies that incorporate genetic and other risk factors, particularly among Hispanic women, are …

  15. What is a Tyrer-Cuzick score and what do the results mean?

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