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- New treatments for endometrial cancer include123:
- New drugs
- New combinations of drugs
- Chemotherapy drugs
- Immunotherapies
- Targeted therapies
- Surgery, which is the standard treatment for early-stage endometrial cancer
- Radiation with or without chemotherapy, hormone therapy, and some targeted therapies, depending on the stage of disease and other factors
- A new combination therapy for advanced or recurrent endometrial cancer has been approved by the FDA. Patients with advanced or recurrent endometrial cancer who are mismatch repair-deficient (dMMR) or microsatellite instability-high (MSI-H) can now be prescribed the immune checkpoint inhibitor, dostarlimab-gxly (brand name Jemperli) and chemotherapy3.
Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.New drugs, new combinations of drugs, chemotherapy drugs, immunotherapies, and targeted therapies are being researched for use in women with advanced endometrial cancer. The use of chemotherapy, with or without radiation after surgery is also being studied.www.cancer.org/cancer/types/endometrial-cancer/…Surgery is the standard treatment for early-stage endometrial cancer. Additional treatment, depending on the stage of disease and other factors, may include radiation with or without chemotherapy, hormone therapy, immunotherapy, and some targeted therapies. Several new treatments for advanced disease have become available.www.cancer.gov/types/uterine/researchNew Treatment Option For Advanced Or Recurrent Endometrial Cancer
- A new combination therapy for advanced or recurrent endometrial cancer has been approved by the FDA.
www.survivornet.com/articles/jemperli-dostarlimab … - People also ask
Expanded Role for Immunotherapy to Treat Endometrial Cancer
Two large clinical trials show that adding immunotherapy to chemotherapy improves progression-free survival for women with advanced or recurrent endometrial cancer. The trials used different immune checkpoint inhibitors, pembrolizumab and dostarlimab, and found the greatest benefit for tumors with … See more
The number of US women diagnosed each year with endometrial cancer has been steadily growing, and it is the only gynecologic cancer with rising death rates. The increased … See more
The trial that used pembrolizumab, called NRG-GY018, included more than 800 participants. They were randomly assigned to receive either pembrolizumab plus chemotherapy for about 6 months, followed by “maintenancetreatment” with pembrolizumab … See more
Multiple experts on gynecologic cancers agreed that, for people with advanced or recurrent endometrial cancer who have dMMR tumors, adding either pembrolizumab or dostarlimab to chemotherapy should be the new standard first-line treatment. … See more
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