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- Stelara is a biologic medicine that targets proteins called interleukins (IL)-12 and IL-2312. These proteins contribute to the long-lasting inflammation that is a main feature of ulcerative colitis1. Stelara is effective in treating ulcerative colitis in adults3. It is an immunosuppressant medication that works by binding to two inflammatory cytokines, IL-12 and IL-23, which have been identified as important contributors to chronic inflammation2. Stelara is given every 8 weeks for Crohn’s disease and ulcerative colitis2.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Stelara works by targeting proteins called interleukins (IL)-12 and IL-23. These proteins are thought to contribute to the long-lasting inflammation that is a main feature of ulcerative colitis. Stelara is a biologic medicine. Biologics target proteins, enzymes and other molecules that cause inflammation, pain and destruction.www.drugs.com/medical-answers/stelara-treat-ulce…Stelara is an immunosuppressant medication that works by binding to two inflammatory cytokines, IL-12 and IL-23, which have been identified as important contributors to chronic inflammation. Stelara is given every 8 weeks for Crohn’s disease and ulcerative colitis and every 12 weeks for people with psoriasis.www.drugs.com/tips/stelara-patient-tipsIn clinical studies, Stelara was effective in treating ulcerative colitis in adults. To learn how the drug performed in these studies, see Stelara’s prescribing information. Additionally, guidelines from the American Gastroenterological Association suggest Stelara as a treatment option for adults with moderate to severe ulcerative colitis.www.medicalnewstoday.com/articles/326482
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