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  2. Property of a cell

    Excitability is a property of a cell, allowing it to respond to stimulation by rapid changes in membrane potential produced by ion fluxes across the plasma membrane.
    www.nature.com/subjects/excitability
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    What is excitability based on?Honorio T. Benzon, in Raj's Practical Management of Pain (Fourth Edition), 2008 The excitability of neurons, the ability to generate a large, rapid change of membrane voltage in response to a very small stimulus, is based on the action potential.
    What is cardiac excitability?Cardiac excitability refers to the amount of inward current needed by myocytes or myocardial cells, cells in the muscular middle layer of the heart, to depolarize or generate an action potential. Whether or not it depolarizes depends on if its voltage-gated «sodium ion channels are excitable or not.
    When is reduced excitability observed?Reduced excitability is physiologically observed during the relative refractory period (occurring during phase 3 of the action potential, before full recovery of E m ). At less negative potentials of the cell membrane, a portion of Na + channels will still be inactivated and unavailable for activation.
    What is the role of excitability in neurons?The role of excitability in neurons is well established: it is harnessed both to send information (in the form of the action potential) and to decide whether information should be sent.
     
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    Membrane potential - Wikipedia

    Cell excitability is the change in membrane potential that is necessary for cellular responses in various tissues. Cell excitability is a property that is induced during early embriogenesis. Excitability of a cell has also been defined as the ease with which a response may be triggered. See more

    Membrane potential (also transmembrane potential or membrane voltage) is the difference in electric potential between the interior and the … See more

    Graded potentials image

    When the membrane potential of a cell goes for a long period of time without changing significantly, it is referred to as a resting potential or resting voltage. This term is used for the … See more

    From the viewpoint of biophysics, the resting membrane potential is merely the membrane potential that results from the membrane permeabilities that predominate when … See more

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    The membrane potential in a cell derives ultimately from two factors: electrical force and diffusion. Electrical force arises from the mutual attraction between particles with opposite … See more

    As explained above, the potential at any point in a cell's membrane is determined by the ion concentration differences between the intracellular and extracellular areas, and by the … See more

    While cells expend energy to transport ions and establish a transmembrane potential, they use this potential in turn to transport other ions … See more

     
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