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WebYONDELIS® is the first FDA-approved treatment for advanced soft tissue sarcoma. Learn about efficacy, side effects, risks, safety, and more.
Treatment Considerations
Percentages based on incidence data from 1978-2001 collected in the 9 …
Efficacy
YONDELIS ® (trabectedin) study design 1. YONDELIS ® was studied in a phase 3 …
Safety
The safety of YONDELIS ® was evaluated in 755 patients. YONDELIS ® was …
Dosing and Administration
Recommended starting dose and schedule for administering YONDELIS® …
MOA
YONDELIS ® (trabectedin) is an alkylating drug that binds guanine residues in the …
Janssen CarePath
Affordability support to help your patients start and stay on the Janssen treatment …
Resources
Resources for health care professionals and doctors prescribing YONDELIS® …
Patients
YONDELIS ® is a prescription medicine …
WebYondelis is indicated for the treatment of patients with advanced soft-tissue sarcoma, after failure of anthracyclines and ifosfamide, or who are unsuited to receive these agents. Efficacy data are based mainly on liposarcoma and leiomyosarcoma patients. Yondelis in combination with pegylated liposomal doxorubicin (PLD) is indicated for the ...
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WebYONDELIS (trabectedin) for injection is supplied as a sterile lyophilized white to off-white powder/cake in a single-dose vial. Each single-dose vial contains 1 mg of trabectedin, 27.2 mg potassium dihydrogen phosphate, 400 mg sucrose, and phosphoric acid and potassium hydroxide (for pH adjustment to 3.6 – 4.2).
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- Generic Name: Trabectedin
Trabectedin is used to treat certain types of cancer.
May Treat: Leiomyosarcoma · Liposarcoma
Drug Class: Antineoplastic-Alkylating Agent-Tetrahydroisoquinoline and Derivatives
Availability: Prescription Required
Pregnancy: Consult your doctor. This medication may be harmful to an unborn child.
Lactation: This drug should not be given to breastfeeding mothers
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Manufacturer: JANSSEN PRODUCT
PrecautionsFor informational purposes only. Consult a medical professional for advice.
Source: First Databank Learn more
Trabectedin, sold under the brand name Yondelis, is an antitumor chemotherapy medication for the treatment of advanced soft-tissue sarcoma and ovarian cancer.
The most common adverse reactions include nausea, fatigue, vomiting, constipation, decreased appetite, diarrhea, peripheral edema, dyspnea, and h…Wikipedia · Text under CC-BY-SA license- Estimated Reading Time: 9 mins
Yondelis - Chemocare
WebYondelis - Trabectedin Injection What is this medication? TRABECTEDIN (tra BEK te din) treats sarcoma, a cancer that occurs in bone and connective tissues, such as fat, muscle, and blood vessels.
How Does YONDELIS® Infusion Therapy Work? | YONDELIS®
WebYONDELIS ® is given by an intravenous (IV) infusion into a vein over 24 hours. To help avoid irritation at the site where it is infused, YONDELIS ® is given to you into a large vein through a type of IV line called a central venous line. YONDELIS ® is usually given every 3 …
Yondelis® Approved for Treatment of Soft Tissue …
WebCancerConnect. Aug 2, 2018. Home. Sarcoma. The United States Food and Drug Administration (FDA) approved the chemotherapy agent, Yondelis® (trabectedin), for the treatment of liposarcoma and …
WebYondelis is used to treat adults with two types of cancer: • advanced soft-tissue sarcoma, a type of cancer that develops from the soft, supporting tissues of the body. ‘Advanced’ means that the cancer has started to spread. Yondelis is used when treatment with anthracyclines and ifosfamide (other cancer medicines) have stopped working ...
WebMedscape - Soft tissue sarcoma dosing for Yondelis (trabectedin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.
Yondelis: Uses, Dosage & Side Effects - Drugs.com
WebApr 22, 2024 · Yondelis (trabectedin) is used to treat liposarcoma or leiomyosarcoma, two common subtypes of soft tissue sarcoma. Includes Yondelis side effects, interactions and indications.
Welcome to Janssen CarePath | Janssen CarePath for …
WebApr 9, 2024 · YONDELIS ® (trabectedin) is indicated for the treatment of patients with unresectable or metastatic liposarcoma or leiomyosarcoma who received a prior anthracycline‑containing regimen. IMPORTANT SAFETY INFORMATION. CONTRAINDICATIONS— YONDELIS ® is contraindicated in patients with known …
WebFor the treatment of ovarian cancer Yondelis is administered every three weeks as a 3-hour infusion at a dose of 1.1 mg/m2, immediately after PLD 30 mg/m2. To minimize the risk of PLD infusion reactions, the initial dose is administered at a rate no greater than 1 mg/minute. If no infusion reaction is observed, subsequent PLD infusions may be ...
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Simi Valley, California - Wikipedia
WebSimi Valley (/ ˈ s iː m iː / ⓘ; Chumash: Shimiyi) is a city in the valley of the same name in the southeast region of Ventura County, California, United States.Simi Valley is 40 miles (65 km) from Downtown Los Angeles, making it part of the Greater Los Angeles Area.The city borders Thousand Oaks, Moorpark, and the Chatsworth neighborhood of Los Angeles.
Interactive Map of the San Andreas Fault - Thule Scientific
WebInteractive Map of the San Andreas Fault - Thule Scientific. Zoom and pan as you please! From space, the San Andreas Fault and its attending landforms are beautifully revealed.
Yondelis | European Medicines Agency
WebOverview. On 24 July 2003 the Committee for Proprietary Medicinal Products (CPMP) adopted a negative opinion, recommending not to grant a marketing authorisation for the medicinal product Yondelis, 0.25 mg and 1 mg, powder for concentrate for solution for infusion intended for patients with advanced soft tissue sarcoma (STS), having failed …
WebYONDELIS (trabectedin) for injection is supplied as a sterile lyophilized white to off-white powder/cake in a single-dose vial. Each single-dose vial contains 1 mg of trabectedin, 27.2 mg potassium dihydrogen phosphate, 400 mg sucrose, and phosphoric acid and potassium hydroxide (for pH adjustment to 3.6 – 4.2).
MICHELIN Simi Valley map - ViaMichelin
WebSimi Valley is located in: United States Dean Pass Simi Valley. Find detailed maps for United States Dean Pass Simi Valley on ViaMichelin, along with road traffic, the option to book accommodation and view information on MICHELIN restaurants for - Simi Valley.
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